UPSK RNA

The Upstream pseudoknot (UPSK) domain is an RNA element found in the turnip yellow mosaic virus, beet virus Qcite journal |author=Koenig R, Pleij CW, Beier C, Commandeur U |title=Genome properties of beet virus Q, a new furo-like virus from sugarbeet, determined from unpurified virus |journal=J. Gen. Virol. |volume=79 ( Pt 8) |issue= |pages=2027–36 |year=1998 |month=August |pmid=9714254 |doi= |url=http://vir.sgmjournals.org/cgi/pmidlookup?view=long&pmid=9714254] , barley stripe mosaic viruscite journal |author=Solovyev AG, Savenkov EI, Agranovsky AA, Morozov SY |title=Comparisons of the genomic cis-elements and coding regions in RNA beta components of the hordeiviruses barley stripe mosaic virus, lychnis ringspot virus, and poa semilatent virus |journal=Virology |volume=219 |issue=1 |pages=9–18 |year=1996 |month=May |pmid=8623558 |doi=10.1006/viro.1996.0217 |url=] and tobacco mosaic viruscite journal |author=Felden B, Florentz C, Giegé R, Westhof E |title=A central pseudoknotted three-way junction imposes tRNA-like mimicry and the orientation of three 5' upstream pseudoknots in the 3' terminus of tobacco mosaic virus RNA |journal=RNA |volume=2 |issue=3 |pages=201–12 |year=1996 |month=March |pmid=8608444 |pmc=1369363 |doi= |url=http://www.rnajournal.org/cgi/pmidlookup?view=long&pmid=8608444] , which is thought to be needed for efficient transcription. Disruption of the pseudoknot structure gives rise to a 50% drop in transcription efficiency. [cite journal | last = Deiman | first = BA | coauthors = Kortlever RM, Pleij CW | year = 1997 | title = The role of the pseudoknot at the 3' end of turnip yellow mosaic virus RNA in minus-strand synthesis by the viral RNA-dependent RNA polymerase | journal = J Virol | volume = 71 | pages = 5990–5996 | pmid = 9223489] This element acts in conjunction with the Tymovirus/Pomovirus tRNA-like 3' UTR element to enhance translation. [cite journal | last = Matsuda | first = D | coauthors = Dreher TW | year = 2004 | title = The tRNA-like structure of Turnip yellow mosaic virus RNA is a 3'-translational enhancer | journal = Virology | volume = 321 | pages = 36–46 | pmid = 15033563 | doi = 10.1016/j.virol.2003.10.023]

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