Spot 42 RNA

Spot 42 RNA

The Spot 42 (spf) RNA is a non-coding RNA molecule discovered almost three decades ago. "Escherichia coli" Spot 42 RNA is 109 nucleotides in length. Its physiological role has remained obscure, but Spot 42 seems to have a regulatory role on the galactose operon. [cite journal | last = Moller | first = T | coauthors = Franch T, Udesen C, Gerdes K, Valentin-Hansen P | year = 2002 | title = Spot 42 RNA mediates discoordinate expression of the "E. coli" galactose operon | journal = Genes Dev | volume = 16 | pages = 1696–1706 | pmid = 12101127 | doi = 10.1101/gad.231702] It is proposed that Spot 42 acts by an antisense mechanism where the RNA binds to the galK translation initiator region. Changes in Spot 42 levels are implicated in affecting the adjacent DNA polymerase I levels. [cite journal | last = Polayes | first = DA | coauthors = Rice PW, Dahlberg JE | year = 1988 | title = DNA polymerase I activity in Escherichia coli is influenced by spot 42 RNA | journal = J Bacteriol | volume = 170 | pages = 2083–2088 | pmid = 2452153] The Hfq protein has been shown to interact with several small regulatory RNAs in "E. coli", and the protein is required for OxyS, DsrA, RprA and Spot 42 RNA regulation. [cite journal | last = Moller | first = T | coauthors = Franch T, Hojrup P, Keene DR, Bachinger HP, Brennan RG, Valentin-Hansen P | year = 2002 | title = Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction | journal = Mol Cell | volume = 9 | pages = 23–30 | pmid = 11804583 | doi = 10.1016/S1097-2765(01)00436-1]

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • RNA virus — An RNA virus is a virus that has RNA (ribonucleic acid) as its genetic material.[1] This nucleic acid is usually single stranded RNA (ssRNA) but may be double stranded RNA (dsRNA).[2] The ICTV classifies RNA viruses as those that belong to Group… …   Wikipedia

  • RNA — For other uses, see RNA (disambiguation). A hairpin loop from a pre mRNA. Highlighted are the nucleobases (green) and the ribose phosphate backbone (blue). Ribonucleic acid (English pronunciation: /raɪbɵ.njuːˌkleɪ.ɨk ˈæsɪd/), or RNA, is one of… …   Wikipedia

  • RNA — Die Ribonukleinsäure ist eine Nukleinsäure, das heißt eine Kette aus vielen Nukleotiden (ein so genanntes Polynukleotid). Im internationalen und im wissenschaftlichen Sprachgebrauch wird die Ribonukleinsäure mit der englischen Abkürzung RNA… …   Deutsch Wikipedia

  • DNA microarray — A DNA microarray (also commonly known as gene chip, DNA chip, or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes… …   Wikipedia

  • Tethered particle motion — (TPM) is a biophysical method that is used for studying various polymers such as DNA and their interaction with other entities such as proteins. The method allows to measure various physical properties on the substances, as well as to measure the …   Wikipedia

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium

  • Molecular biology — (pronounced /məˈlɛkjʊlər .../) is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology… …   Wikipedia

  • Taura syndrome — Taxobox virus group = iv familia = Discistroviridae species = Taura syndrome virus The controversyTaura syndrome (TS) was first described in Ecuador during the summer of 1992. In March 1993, it returned as a major epidemic and was the object of… …   Wikipedia

  • List of genetics-related topics — This is a list of terms related to genetics. NOTOC # * 3 end * 5 end A * Acentric chromosome * Achondroplasia * Active site * Adam s Curse * Adaptation * Adenine * Adenosine * Adenovirus * Adenosine diphosphate (ADP) * Ala * Alagille syndrome *… …   Wikipedia

  • Evidence of common descent — The wide range of evidence of common descent of living things strongly indicates the occurrence of evolution and provides a wealth of information on the natural processes by which the variety of life on Earth developed, supporting the modern… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”