Small nucleolar RNA SNORA48

Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned by Kiss et al. (2004) [cite journal | last = Kiss | first = AM | coauthors = Jady BE, Bertrand E, Kiss T | year = 2004 | title = Human box H/ACA pseudouridylation guide RNA machinery | journal = Mol Cell Biol. | volume = 24 | pages = 5797–5807 | pmid = 15199136 | doi = 10.1128/MCB.24.13.5797-5807.2004] from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U3797 of 28S rRNA. The pseudouridylation of this residue was previously reported by Ofengand and Bakin (1997) [cite journal | last = Ofengand | first = J | coauthors = Bakin A | year = 1997 | title = Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts | journal = J Mol Biol. | volume = 266 | pages = 246–268 | pmid = 9047361 | doi = 10.1006/jmbi.1996.0737] . The H/ACA box snoRNAs ACA48 and U67, and the C/D box snoRNA mgU6-77 share the same host gene (EIF4A1).

References

External links

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* [http://www-snorna.biotoul.fr/plus.php?id=ACA48 snoRNAbase entry for ACA48.]