Retrovirus direct repeat 1 (dr1)

Retrovirus direct repeat 1 (dr1)

The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA packaging although this may not be its only role. [cite journal | last = Aschoff | first = JM | coauthors = Foster D, Coffin JM | year = 1999 | title = Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect | journal = J Virol | volume = 73 | pages = 7421–7429 | pmid = 10438832]

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