Fluid attenuated inversion recovery
- Fluid attenuated inversion recovery
Fluid Attenuated Inversion Recovery (FLAIR) is a pulse sequence used in Magnetic Resonance Imaging which was invented by Dr Graeme Bydder.
The pulse sequence is an inversion recovery technique that nulls fluids. For example, it can be used in brain imaging to suppress Cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hypertintense lesions, such as multiple sclerosis (MS) plaques [Bakshi R, Ariyaratana S, Benedict RH, Jacobs L. Fluid-attenuated inversion recovery magnetic resonance imaging detects cortical and juxtacortical multiple sclerosis lesions PMID 11346369] .
By carefully choosing the TI, the signal from any particular tissue can be nulled. The appropriate TI depends on the tissue via the formula:
TI = ln2 * T1
One should typically yield a TI of 70% of T1. In the case of CSF suppression, one aims for T2 weighted images.
ee also
*Relaxation (NMR)
Further reading
*McRobbie D., et al. "MRI, From picture to proton." 2003 p.40-42
*Hashemi Ray, et al. "MRI, The Basics" 2ED. 2004. p.272
References
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