VS ribozyme

VS ribozyme

The Varkud satellite (VS) ribozyme is an RNA enzyme that carries out the cleavage of a phosphodiester bond [cite journal |author=Saville BJ, Collins RA |title=A site-specific self-cleavage reaction performed by a novel RNA in Neurospora mitochondria |journal=Cell |volume=61 |issue=4 |pages=685–696 |year=1990 |doi=10.1016/0092-8674(90)90480-3] .

tructure

The VS ribozyme is composed of 5 helices that form an H shape (helices II to VI). The first helix (I) contains the substrate cleavage site in the stem-loop.

pecies Distribution

The VS ribozyme has only been found in DNA of Neurospora mitochondria.

References


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