- CYP51A1
protein
Name=cytochrome P450, family 51, subfamily A, polypeptide 1
caption=
width=
HGNCid=2649
Symbol=CYP51A1
AltSymbols=CYP51
EntrezGene=1595
OMIM=601637
RefSeq=NM_000786
UniProt=Q16850
PDB=
ECnumber=1.14.13.70
Chromosome=7
Arm=q
Band=21.2
LocusSupplementaryData=-21.3CYP51A1 (or lanosterol 14 alpha-demethylase) is a
cytochrome P450 (family 51, subfamily A, polypeptide 1) which convertslanosterol tocholesterol .It is a target for
antifungal drugs, inhibiting the production ofergosterol . Over-expression of CYP51A1 can lead to resistance to these antifungals.cite journal |author=Vanden Bossche H, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D |title=Antifungal drug resistance in pathogenic fungi |journal=Med. Mycol. |volume=36 Suppl 1 |issue= |pages=119–28 |year=1998 |pmid=9988500 |doi= |url=]ee also
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Antifungal drug References
External links
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