Jacqueline Barton

Infobox Scientist


image_width = 150px
name=Jacqueline K. Barton
birth_date=
birth_place=New York City
nationality=USA
field=Chemistry
alma_mater=Barnard College
Columbia
work_institution=Bell Labs
Yale
Hunter College
Columbia
Caltech
doctoral_supervisor=S.J. Lippard
doctoral_students=Anna Marie Pyle
societies=American Academy of Arts and Sciences
American Philosophical Society
National Academy of Sciences
prizes=Alan T. Waterman Award of the National Science Foundation (1985)
Fresenius Award (1986)
American Chemical Society Eli Lilly Award in Biological Chemistry(1987)American Chemical Society Award in Pure Chemistry (1988)The Mayor of New York's Award in Science and Technology (1988)American Chemical Society Baekeland Medal (1991)
MacArthur Foundation Fellowship (1991)American Chemical Society Garvan Medal (1992)American Chemical Society Tolman Medal (1994)Havinga Medal (1995)Paul Karrer Medal (1996)American Chemical Society Nichols Medal (1997)
Weizmann Women & Science Award (1998)ACS Ronald Breslow Award in Biomimetic Chemistry (2003)
ACS Gibbs Medal (2006)

Professor Jacqueline K. Barton is the Arthur and Marian Hanisch Memorial professor of Chemistry at California Institute of Technology. The primary focus of her research is transverse electron transport along double-stranded DNA, its implications in the biology of DNA damage and repair, and its potential for materials sciences applications. She is married to fellow Caltech chemist Peter Dervan.

Education

Barton received her B.A. (summa cum laude) from Barnard College in 1974. She went on to graduate study at Columbia University, where she studied inorganic chemistry under the supervision of S.J. Lippard. After earning her Ph.D. from Columbia in 1979, she held post-doctoral appointments at Bell Labs and Yale University, where she worked with R.G. Shulman.

elected publications

* cite journal
title=Direct Electrochemistry of Endonuclease III in the Presence and Absence of DNA
first=A.A.
last=Gorodetsky
coauthors=A.K. Boal, and J.K. Barton
journal=J. Am. Chem. Soc.
volume=128
pages=12082–12083
year=2006
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A253.pdf
doi=10.1021/ja064784d
format=abstract

* cite journal
title=Electrochemistry Using Self-Assembled DNA Monolayers on Highly Oriented Pyrolytic Graphite
first=A.A.
last=Gorodetsky
coauthors=J.K. Barton
journal=Langmuir
volume=22
pages=7917–7922
year=2006
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A252.pdf
doi=10.1021/la0611054
format=abstract

* cite journal
title=Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF Mass Spectrometry
first=J.
last=Brunner
coauthors=J.K. Barton
journal=J. Am. Chem. Soc.
volume=128
pages=6772–6773
year=2006
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A251.pdf
doi=10.1021/ja0612753
format=abstract

* cite journal
title=Electron Trap for DNA-bound Repair Enzymes: A Strategy For DNA-mediated Signaling
first=E.
last=Yavin
coauthors=E.D.A. Stemp, V.L. O'Shea, S.S. David and J.K. Barton
journal=Proc. Nat. Acad. Sci. USA
volume=103
pages=3610–3614
year=2006
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A250.pdf
doi=10.1073/pnas.0600239103
format=abstract
pmid=16505354

* cite journal
title=A Mismatch-Selective Bifunctional Rhodium-Oregon Green Conjugate: A Fluorescent Probe for Mismatched DNA
first=B.M.
last=Zeglis
coauthors=J.K. Barton
journal=J. Am. Chem. Soc.
volume=128
pages=5654–5655
year=2006
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A249.pdf
doi=10.1021/ja061409c
format=abstract

* cite journal
title=Sequence Dependence of Charge Transport through DNA Domains
first=F.
last=Shao
coauthors=K. Augustyn and J.K. Barton
journal=J. Am. Chem. Soc.
volume=127
pages=17445–17452
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A248.pdf
doi=10.1021/ja0563399
format=abstract

* cite journal
title=Reductive and Oxidative DNA Damage by Photoactive Platinum(II) Intercalators
first=W.
last=Lu
coauthors=D.A. Vicic, and J.K. Barton
journal=Inorg. Chem.
volume=44
pages=7970–7980
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A247.pdf
doi=10.1021/ic051124l
format=abstract

* cite journal
title=DNA Charge Transport Leading to Disulfide Bond Formation
first=T.
last=Takada
coauthors=J.K. Barton
journal=J. Am. Chem. Soc.
volume=127
pages=12204–12205
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A246.pdf
doi=10.1021/ja054306n
format=abstract

* cite journal
title=Electrochemically Monitoring DNA Repair by Photolyase
first=M.C.
last=DeRosa
coauthors=A. Sancar, and J.K. Barton
journal=Proc. Nat. Acad. Sci. USA
volume=102
pages=10788–10792
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A245.pdf
doi=10.1073/pnas.0503527102
format=abstract
pmid=16043698

* cite book
chapter=Sequence-Dependent DNA Dynamics: The Regulator of DNA-Mediated Charge Transport
first=M.A.
last=O'Neill
coauthors=J.K. Barton
title=Charge Transfer in DNA: From Mechanism to Application
editor=ed. H.A. Wagenknecht
publisher=Wiley-VCH
pages=27-75
year=2005

* cite journal
title=DNA Electrochemistry through the Base Pairs Not the Sugar-Phosphate Backbone
first=T.
last=Liu
coauthors=J.K. Barton
journal=J. Am. Chem. Soc.
volume=127
pages=10160–10161
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A244.pdf
doi=10.1021/ja053025c
format=abstract

* cite journal
title=DNA-Bound Redox Activity of DNA Repair Glycosylases Containing [4Fe-4S] Clusters
first=A.K.
last=Boal
coauthors=E. Yavin, O.A. Lukianova, V.L. O'Shea, S.S. David, and J.K. Barton
journal=Biochem.
volume=44
pages=8397–8407
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A243.pdf
doi=10.1021/bi047494n
format=abstract

* cite journal
title=Electrochemical Detection of Lesions in DNA
first=A.K.
last=Boal
coauthors=J.K. Barton
journal=Bioconj. Chem.
volume=16
pages=312–321
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A242.pdf
doi=10.1021/bc0497362
format=abstract

* cite journal
title=Protein-DNA Charge Transport: Redox Activation of a DNA Repair Protein by Guanine Radical
first=E.
last=Yavin
coauthors=A.K. Boal, E.D.A. Stemp, E.M. Boon, A.L. Livingston, V.L. O'Shea, S.S. David, and J.K. Barton
journal=Proc. Nat. Acad. Sci. USA
volume=102
pages=3546–3551
year=2005
url=http://www.its.caltech.edu/~jkbgrp/abstracts/A241.pdf
doi=10.1073/pnas.0409410102
format=abstract
pmid=15738421

External links

* [http://www.its.caltech.edu/~jkbgrp/TheBoss.htm Personal biography]
* [http://www.its.caltech.edu/~jkbgrp/ Barton Research Group]

Persondata
NAME= Barton, Jacqueline K.
ALTERNATIVE NAMES=
SHORT DESCRIPTION=American chemist
DATE OF BIRTH=
PLACE OF BIRTH=New York City
DATE OF DEATH=
PLACE OF DEATH=