Streptomyces toxytricini

Streptomyces toxytricini

Taxobox
color = lightgrey
name = "Streptomyces toxytricini"
domain = Bacteria
phylum = Actinobacteria
ordo = Actinomycetales
familia = Streptomycetaceae
genus = "Streptomyces"
species = "S. toxytricini"
binomial = "Streptomyces toxytricini"
binomial_authority = Preobrazhenskaya & Sveshnikova 1957

"Streptomyces toxytricini" is a Gram-positive bacterium belonging to the genus "Streptomyces". It produces the pancreatic lipase inhibitor lipstatin, [cite journal |author=Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H |title=Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity |journal=J Antibiot (Tokyo) |volume=40 |issue=8 |pages=1081–5 |year=1987 |pmid=3680018] of which the antiobesity drug orlistat is a derivative.cite journal | author = Barbier P, Schneider F | title = Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin | journal = Helvetica Chimica Acta | volume = 70 | issue = 1 | pages = 196–202 | year = 1987 | doi = 10.1002/hlca.19870700124]

References


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