Coactivation (Transcription)

Coactivation (Transcription)

Coactivation is a process by which the transcription of RNA is increased. Proteins called coactivators are recruited to DNA-binding transcription factors through their activation domains and increase transcription by relaxing the chromatin structure to allow greater access to a gene or by bringing in components of the basal transcription complex needed for transcription to occur. Examples of coactivators are CBP, p300, and SWI/SNF.[1]

References

  1. ^ Spiegelman BM, Heinrich R (October 2004). "Biological control through regulated transcriptional coactivators". Cell 119 (2): 157–67. doi:10.1016/j.cell.2004.09.037. PMID 15479634. 

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Coactivation — may mean: Coactivation (Transcription), a process by which RNA transcription is increased Coactivation (Muscular), a process in which a muscle is activated in tandem with another muscle This disambiguation page lists articles associated with the… …   Wikipedia

  • coactivation — noun a) Activation of two or more things together b) A process wherein RNA transcription is increased by a coactivator protein See Also: activation, coactivate, coactivity, cocontraction …   Wiktionary

  • CREB-binding protein — See also: p300 CBP coactivator family CREB binding protein PDB rendering based on 1f81 …   Wikipedia

  • MEF2C — Myocyte enhancer factor 2C PDB rendering based on 1c7u …   Wikipedia

  • EP300 — See also: p300 CBP coactivator family E1A binding protein p300 PDB rendering based on 1f81 …   Wikipedia

  • EVI1 — Ecotropic viral integration site 1 is a human protein encoded by the EVI1 gene. EVI1 was first identified as a common retroviral integration site in AKXD murine myeloid tumors. It has since been identified in a plethora of other organisms, and… …   Wikipedia

  • MyoD — Myogenic differentiation 1 PDB rendering based on 1mdy …   Wikipedia

  • NCOA6 — Nuclear receptor coactivator 6 Identifiers Symbols NCOA6; AIB3; ASC2; KIAA0181; NRC; PRIP; RAP250; TRBP External IDs …   Wikipedia

  • Thyroid hormone receptor beta — Thyroid hormone receptor, beta (erythroblastic leukemia viral (v erb a) oncogene homolog 2, avian) PDB rendering based on 1bsx …   Wikipedia

  • RNF4 — Ring finger protein 4, also known as RNF4, is a human gene.cite web | title = Entrez Gene: RNF4 ring finger protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6047| accessdate = ] The protein encoded …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”