Sarett oxidation

Sarett oxidation

The Sarett oxidation is the oxidation of an alcohol to a ketone or an aldehyde using chromic oxide and pyridine. Primary alcohols will only be oxidised to the aldehyde and not on to carboxylic acids.

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The reagent is named after the American chemist Lewis Hastings Sarett (1917– 1999).

ee also

* Collins reagent
* Pyridinium chlorochromate
* Jones oxidation

References

#cite journal
title = Approaches to the Total Synthesis of Adrenal Steroids.1 V. 4b-Methyl-7- ethylenedioxy-1,2,3,4,4aα,4b,5,6,7,8,10,10a β-dodecahydrophenanthrene-4 β-ol-1-one and Related Tricyclic Derivatives
author = G. I. Poos, G. E. Arth, R. E. Beyler, and L. H. Sarett
journal = Journal of the American Chemical Society
volume = 75
issue = 2
pages = 422 - 429
year = 1953
url =
doi = 10.1021/ja01098a049
#J. R. Holum, J. Org. Chem. 26, 4814 (1961)
#E. J. Kris, Chemistry & Industry (London) 1961 1834)
#V. I. Stenberg, and R. J. Perkins, J. Org. Chems. 28, 323 (1963)
#P. G. Gassman and P. G. Pape, J. Org. Chem. 29, 160 (1964).

External links

* [http://www.chempensoftware.com/reactions/RXN348.htm Sarett oxidation]


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  • Sarett-Oxidation — Sa|rett O|xi|da|ti|on [ særət ; nach dem amer. Chemiker L. H. Sarett (1917–1999)]: Oxidation primärer bzw. sekundärer Alkohole zu Aldehyden bzw. Ketonen mittels Chrom(VI) oxid Pyridin Komplex (vgl. Collins Reagenz) …   Universal-Lexikon

  • Lewis Hastings Sarett — Infobox Person name = Lewis Hastings Sarett image size = caption = birth date = December 22, 1917 birth place = Champaign, Illinois death date = November 29, 1999 (age|1917|12|22|1999|11|29) death place = Viola, Idaho occupation = Organic chemist …   Wikipedia

  • Oxydation de Sarett — L oxydation de Sarett est l oxydation d un alcool en cétone ou en aldéhyde par un complexe de trioxyde de chrome et de pyridine dans la pyridine[1]. Cette réaction porte le nom du chimiste américain Lewis Hastings Sarett (1917 1999) qui l a… …   Wikipédia en Français

  • Jones oxidation — The Jones oxidation is a chemical reaction described as the chromic acid oxidation of primary and secondary alcohols to carboxylic acids and ketones, respectively. [cite journal | author = Bowden, K.; Heilbron, I. M.; Jones, E. R. H | journal = J …   Wikipedia

  • List of organic reactions — Well known reactions and reagents in organic chemistry include Contents: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z    See also   Ext …   Wikipedia

  • Collins reagent — is the complex of chromium(VI) oxide with pyridine in dichloromethane.[1][2] It is used to selectively oxidize primary alcohols to the aldehyde, and will tolerate many other functional groups within the molecule. It can be used as an alternative… …   Wikipedia

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