Haptotaxis

Haptotaxis

Haptotaxis is the directional motility or outgrowth of cells, e.g. in the case of axonal outgrowth, usually up a gradient of cellular adhesion sites or substrate-bound chemoattractants. These gradients are naturally present in the extracellular matrix (ECM) of the body during processes such as angiogenesis or artificially present in biomaterials where gradients are established by altering the concentration of adhesion sites on a polymer substrate. [cite journal | author= McCarthy JB, Palm SL, Furcht LT.| title= Migration by haptotaxis of a Schwann cell tumor line to the basement membrane glycoprotein laminin
journal= J Cell Biol | year= 1983| volume=97(3)| pages= 772–7| doi= 10.1083/jcb.97.3.772| pmid= 6885918] [cite journal | author= Cattaruzza S, Perris R.
title= Proteoglycan control of cell movement during wound healing and cancer spreading| journal= Matrix Biol | year= 2005| volume=24(6)| pages= 400–17
doi= 10.1016/j.matbio.2005.06.005]

References

External links

* "Cellular Migration" University of California, Berkeley, 2003. University of California, Berkeley Cell and Tissue Engineering website. http://ctelab.berkeley.edu/research/migration.htm


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