Pseudovridae

The type species "Saccharomyces cerevisiae Ty1 virus", from the genus "pseudovirus" and the type "species" "Drosophila melanogaster copia virus" from the genus "Hemivirus", both belong to the "Pseudoviridae" family. The "Hemivirus" and "Pseudovirus" constitute the two genera of "Pseudoviridae"."Pseudoviridae" is classified under group VI RNA Reverse Transcribing Viruses and infect fungal, or invertebrate. The genome of viruses from this family is unsegmented, -RT, positive-sense, single-stranded RNA and is 4200-9700 nucleotides long. The genome encodes structural proteins and non-structural proteins which codes for an RNA-dependent DNA polymerase, replicase, and reverse transcriptase for the reverse transcription step during replication.Its genome integrates into the host genome and gets transcribed by host cell enzymes such as eukaryotic nuclear RNA polymerase II. Genome replication takes place in the host cytoplasm, or the nucleus and assembly can occur in the cytoplasm, or in the nucleus.The viral capsid is unenveloped and looks roughly spherical. The capsid is round with icosahedral symmetry (T=3 and 4), and is also isometric to quasi-isometric and has a diameter of 30-50 nm. LRT- retrotransposons are poorly characterized and lipids are not reported"Pseudoviridae" comprises highly divergent members and most "Pseudoviridae" encode Gag and Pol on a single open reading frame.

External links

* [http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/00.097.htm ICTV Pseudoviridae Page]