Synaptojanin

Synaptojanin

protein
Name=synaptojanin 1
caption=


width=
HGNCid=11503
Symbol=SYNJ1
AltSymbols=
EntrezGene=8867
OMIM=604297
RefSeq=NM_003895
UniProt=O43426
PDB=
ECnumber=
Chromosome=21
Arm=q
Band=22.2
LocusSupplementaryData=
protein
Name=synaptojanin 2
caption=


width=
HGNCid=11504
Symbol=SYNJ2
AltSymbols=
EntrezGene=8871
OMIM=609410
RefSeq=NM_003898
UniProt=O15056
PDB=
ECnumber=
Chromosome=6
Arm=q
Band=25.3
LocusSupplementaryData=

Synaptojanin is a protein involved in vesicle uncoating in neurons. This is an important regulatory lipid phosphatase. It dephosphorylates the D-5 position phosphate from Phosphatidylinositol (3,4,5)-trisphosphate and Phosphatidylinositol (4,5)-bisphosphate. It belongs to family of 5-phosphatases, which are structurally unrelated to D-3 inositol phosphatases like PTEN.

External links

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