Apolipoprotein D

Apolipoprotein D

Apolipoprotein D, also known as APOD, is a human gene.cite web | title = Entrez Gene: APOD apolipoprotein D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=347| accessdate = ]

PBB_Summary
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summary_text = Apolipoprotein D (Apo-D) is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. It is a glycoprotein of estimated molecular weight 33 KDa. Apo-D is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.cite web | title = Entrez Gene: APOD apolipoprotein D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=347| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rassart E, Bedirian A, Do Carmo S, "et al." |title=Apolipoprotein D. |journal=Biochim. Biophys. Acta |volume=1482 |issue= 1-2 |pages= 185–98 |year= 2000 |pmid= 11058760 |doi=
*cite journal | author=Peitsch MC, Boguski MS |title=Is apolipoprotein D a mammalian bilin-binding protein? |journal=New Biol. |volume=2 |issue= 2 |pages= 197–206 |year= 1991 |pmid= 2083249 |doi=
*cite journal | author=Balbín M, Freije JM, Fueyo A, "et al." |title=Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease. |journal=Biochem. J. |volume=271 |issue= 3 |pages= 803–7 |year= 1990 |pmid= 2244881 |doi=
*cite journal | author=Drayna DT, McLean JW, Wion KL, "et al." |title=Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha 2u-globulin superfamily. |journal=DNA |volume=6 |issue= 3 |pages= 199–204 |year= 1987 |pmid= 2439269 |doi=
*cite journal | author=Drayna D, Scott JD, Lawn R |title=Multiple RFLPs at the human apolipoprotein D (APOD) locus. |journal=Nucleic Acids Res. |volume=15 |issue= 22 |pages= 9617 |year= 1988 |pmid= 2891117 |doi=
*cite journal | author=Drayna D, Fielding C, McLean J, "et al." |title=Cloning and expression of human apolipoprotein D cDNA. |journal=J. Biol. Chem. |volume=261 |issue= 35 |pages= 16535–9 |year= 1987 |pmid= 3453108 |doi=
*cite journal | author=Fielding PE, Fielding CJ |title=A cholesteryl ester transfer complex in human plasma. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=77 |issue= 6 |pages= 3327–30 |year= 1980 |pmid= 6774335 |doi=
*cite journal | author=Schindler PA, Settineri CA, Collet X, "et al." |title=Site-specific detection and structural characterization of the glycosylation of human plasma proteins lecithin:cholesterol acyltransferase and apolipoprotein D using HPLC/electrospray mass spectrometry and sequential glycosidase digestion. |journal=Protein Sci. |volume=4 |issue= 4 |pages= 791–803 |year= 1995 |pmid= 7613477 |doi=
*cite journal | author=Yang CY, Gu ZW, Blanco-Vaca F, "et al." |title=Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links. |journal=Biochemistry |volume=33 |issue= 41 |pages= 12451–5 |year= 1994 |pmid= 7918467 |doi=
*cite journal | author=Holzfeind P, Merschak P, Dieplinger H, Redl B |title=The human lacrimal gland synthesizes apolipoprotein D mRNA in addition to tear prealbumin mRNA, both species encoding members of the lipocalin superfamily. |journal=Exp. Eye Res. |volume=61 |issue= 4 |pages= 495–500 |year= 1996 |pmid= 8549691 |doi=
*cite journal | author=Zeng C, Spielman AI, Vowels BR, "et al." |title=A human axillary odorant is carried by apolipoprotein D. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 13 |pages= 6626–30 |year= 1996 |pmid= 8692868 |doi=
*cite journal | author=Cargill M, Altshuler D, Ireland J, "et al." |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290
*cite journal | author=Liu Z, Chang GQ, Leibowitz SF |title=Apolipoprotein D interacts with the long-form leptin receptor: a hypothalamic function in the control of energy homeostasis. |journal=FASEB J. |volume=15 |issue= 7 |pages= 1329–31 |year= 2001 |pmid= 11344130 |doi=
*cite journal | author=Sánchez D, Ganfornina MD, Martínez S |title=Expression pattern of the lipocalin apolipoprotein D during mouse embryogenesis. |journal=Mech. Dev. |volume=110 |issue= 1-2 |pages= 225–9 |year= 2002 |pmid= 11744388 |doi=
*cite journal | author=Mahadik SP, Khan MM, Evans DR, Parikh VV |title=Elevated plasma level of apolipoprotein D in schizophrenia and its treatment and outcome. |journal=Schizophrenia Research |volume=58 |issue= 1 |pages= 55–62 |year= 2002 |pmid= 12363390 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Desai PP, Hendrie HC, Evans RM, "et al." |title=Genetic variation in apolipoprotein D affects the risk of Alzheimer disease in African-Americans. |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=116 |issue= 1 |pages= 98–101 |year= 2003 |pmid= 12497622 |doi= 10.1002/ajmg.b.10798
*cite journal | author=Kang MK, Kameta A, Shin KH, "et al." |title=Senescence-associated genes in normal human oral keratinocytes. |journal=Exp. Cell Res. |volume=287 |issue= 2 |pages= 272–81 |year= 2003 |pmid= 12837283 |doi=
*cite journal | author=Thomas EA, Laws SM, Sutcliffe JG, "et al." |title=Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: no relation to apolipoprotein E expression or genotype. |journal=Biol. Psychiatry |volume=54 |issue= 2 |pages= 136–41 |year= 2003 |pmid= 12873803 |doi=

External links

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