Pancoast tumor

Pancoast tumor


Caption =
DiseasesDB = 31266
ICD10 = ICD10|C|34|1|c|30
ICD9 = ICD9|162.3
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 3418
MeshID = D010178
A pancoast tumor or superior sulcus tumor, is a tumor of the pulmonary apex i.e. a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung.

The growing tumor can cause compression of a brachiocephalic vein, subclavian artery, phrenic nerve, recurrent laryngeal nerve, vagus nerve, or, characteristically, compression of a sympathetic ganglion resulting in a range of symptoms known as Horner's syndrome.

Pancoast tumors are named for Henry Pancoast, a US radiologist, who described them in 1924 and 1932. [WhoNamedIt|synd|2953]


Symptoms can include miosis (constriction of the pupils), anhidrosis (lack of sweating), ptosis (drooping of the eyelid), and in severe cases, a complete Horner's syndrome. In progressive cases, the brachial plexus is also affected, causing pain and weakness in the muscles of the arm and hand. The tumour can also compress the right recurrent laryngeal nerve, a hoarse voice and bovine cough may also occur.

In superior vena cava syndrome, obstruction of the superior vena cava by a tumor (mass effect) causes facial swelling, cyanosis and dilatation of the veins of the head and neck.

A pancoast tumor is an apical tumor that is typically found in conjunction with a smoking history. The clinical signs and symptoms can be confused with neurovascular compromise at the level of the thoracic outlet. The patient's smoking history, rapid onset of clinical signs and symptoms, and pleuritic pain can suggest an apical tumor.


The treatment of a Pancoast lung cancer may differ from that of other types of non-small cell lung cancer. Its position and close proximity to vital structures (such as nerves and spine) may make surgery difficult. As a result, and depending on the stage of the cancer, treatment may involve radiation and chemotherapy given prior to surgery (neoadjuvant treatment).Surgery may consist of the removal of the upper lobe of a lung together with its associated structures (subclavian artery, vein, branches of the brachial plexus, ribs and vertebral bodies), as well as mediastinal lymphadenectomy. Surgical access may be via thoracotomy from the back (Paulson [ "Ann Surg" 1961;54:29–40] ) or the front of the chest (Dartevelle ["J Thorac Cardiovasc Surg" 1993;105:1025–1034] and modifications [ "J Thorac Cardiovasc Surg" 1996;112:558-9.] ["Ann Thorac Surg" 1997;63:563-6] [] )


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Look at other dictionaries:

  • Pancoast, tumor de — oncol. Tumor de los vértices pulmonares que se extiende por los plexos branquiales y destruye las vértebras y costillas; provoca parálisis de los miembros superiores y mucho dolor. Medical Dictionary. 2011 …   Diccionario médico

  • Pancoast-Tumor — Klassifikation nach ICD 10 C34.1 Bösartige Neubildung: Oberlappen ( Bronchus) …   Deutsch Wikipedia

  • Pancoast tumor — A type of lung cancer that begins in the upper part of a lung and spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non small cell cancers. Also called pulmonary sulcus tumor …   English dictionary of cancer terms

  • Pancoast-Tumor — Pan|coast Tumor: das umgebende Knochen und Weichteilgewebe in Mitleidenschaft ziehender expansiver Krebs der Lunge oder der Bronchien im Bereich der Lungenspitze (sog. „Ausbrecherkrebs“) …   Das Wörterbuch medizinischer Fachausdrücke

  • Pancoast tumor — pulmonary sulcus t …   Medical dictionary

  • tumor de Pancoast — Pancoast, tumor de oncol. Tumor de los vértices pulmonares que se extiende por los plexos branquiales y destruye las vértebras y costillas; provoca parálisis de los miembros superiores y mucho dolor. Medical Dictionary. 2011. tumor de Pancoast …   Diccionario médico

  • Pancoast's tumor — or Pancoast tumor n a malignant tumor formed at the upper extremity of the lung …   Medical dictionary

  • Pancoast — Henry Khunrath Pancoast (* 26. Februar 1875 in Philadelphia; † 20. Mai 1939 in Merion, Pennsylvania) war ein US amerikanischer Radiologe. Inhaltsverzeichnis 1 Leben 2 Leistungen 3 Werke …   Deutsch Wikipedia

  • Pancoast's syndrome — Pan·coast s syndrome pan .kōsts n a complex of symptoms associated with Pancoast s tumor which includes Horner s syndrome and neuralgia of the arm resulting from pressure on the brachial plexus Pancoast Henry Khunrath (1875 1939) American… …   Medical dictionary

  • Pancoast syndrome tumor — Pan·coast syndrome, tumor (panґkōst) [Henry Khunrath Pancoast, American radiologist, 1875–1939] see under syndrome, and see pulmonary sulcus tumor, under tumor …   Medical dictionary

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