Hydrastine

Hydrastine

Drugbox
IUPAC_name = "6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinoline-5-yl)-1(3H)-isobenzo furan"


width = 150
CAS_number = 118-08-1
ATC_prefix =
ATC_suffix =
ATC_supplemental =
PubChem = 1309
DrugBank =
C=21 | H=21 | N=1 | O=6
molecular_weight = 383.395
bioavailability =
metabolism = Hepatic
elimination_half-life=
excretion = Renal
pregnancy_category = ?
legal_status =
routes_of_administration =

Hydrastine is a natural alkaloid which was discovered in 1851 by Alfred P. Durand. By hydrolysis of hydrastine one receives Hydrastinine, which was patented by Bayer as a haemostatic drug during 1910s.

It is naturally present in "Hydrastis canadensis" (thus the name) and other plants of the ranunculaceae.


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  • hydrastine — ● hydrastine nom féminin Alcaloïde de l hydrastis, employé comme vasoconstricteur et hémostatique utérin. hydrastine [idʀastin] n. f. ÉTYM. Fin XIXe; de hydraste, lat. sc. hydrastis, du grec hudôr (→ Hydr ), et suff. ine. ❖ ♦ Didact. (chim.,… …   Encyclopédie Universelle

  • Hydrastine — Hy*dras tine, n. (Chem.) An alkaloid, found in the rootstock of the golden seal ({Hydrastis Canadensis}), and extracted as a bitter, white, crystalline substance. It is used as a tonic and febrifuge. [1913 Webster] …   The Collaborative International Dictionary of English

  • hydrastine — [hī dras′tēn΄, hī dras′tin] n. [ModL Hydrastis, name of the genus of herbs (< Gr hydōr, WATER) + INE3] a bitter, crystalline alkaloid, C21H21NO6, extracted from the rootstock of the goldenseal …   English World dictionary

  • hydrastine — /huy dras teen, tin/, n. Pharm. an alkaloid, C21H21NO6, that is extracted from the roots of goldenseal and forms prismatic crystals: used as an astringent and to inhibit uterine bleeding. [1875 80; HYDRAST(IS) + INE2] * * * …   Universalium

  • hydrastine — An alkaloid of hydrastis; an isoquinoline chemically related to narcotine. As the hydrochloride, was used locally in the treatment of catarrhal inflammation of the mucous membranes, and internally in the treatment of gastric inflammation, as …   Medical dictionary

  • hydrastine — n. alkaloid extracted from the root of a North American plant (used in medicine) …   English contemporary dictionary

  • hydrastine — hy·dras·tine …   English syllables

  • hydrastine — /haɪˈdræstin/ (say huy drasteen), / taɪn/ (say tuyn) noun an alkaloid found in the root of goldenseal. {New Latin Hydrastis name of plant + ine2} …  

  • hydrastine — …   Useful english dictionary

  • Hydrastis Canadensis — Hydrastine Hy*dras tine, n. (Chem.) An alkaloid, found in the rootstock of the golden seal ({Hydrastis Canadensis}), and extracted as a bitter, white, crystalline substance. It is used as a tonic and febrifuge. [1913 Webster] …   The Collaborative International Dictionary of English

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