Dalrymple sign

Dalrymple sign

Dalrymple sign is widened palpebral (eyelid) opening, or eyelid spasm, seen in thyrotoxicosis (as seen in Graves' disease but also other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure. Retraction of the upper eyelid, the white of the sclera is visible at the upper margin of the cornea in direct outward stare.

Other eye signs described within the symptomology of Graves' disease are Stellwag's sign (rare blinking), Rosenbach's sign (tremor of the eyelids), and Jelink's sign (hyperpigmentation of the eyelid).

ee also

*Graves ophthalmopathy


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