Acetamide

Acetamide

chembox new
ImageFileL1=Acetamide-2D-skeletal.png ImageSizeL1=100px
ImageFileR1=Acetamide-3D-balls.png ImageSizeR1=120px
IUPACName=Acetamide Ethanamide
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Section1 = Chembox Identifiers
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CASNo=60-35-5
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PubChem =
ChemSpiderID = 173
SMILES = CC(=O)N
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Section2 = Chembox Properties
C=2|H=5|N=1|O=1
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Density=1.16 g/cm³
MeltingPt=79-81°C
BoilingPt=222 °C
Solubility=200 g/100 ml
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Solvent = Water
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Section5 = Chembox Pharmacology
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Section6 = Chembox Explosive
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Section7 = Chembox Hazards
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EUClass = Harmful (Xn) Carc3
EUIndex = 616-022-00-4
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NFPA-H = 3
NFPA-F = 1
NFPA-R = 1
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RPhrases = R40
SPhrases = S2, S36/37
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ExternalMSDS = [http://www.physchem.ox.ac.uk/MSDS/AC/acetamide.html External MSDS]
Section8 = Chembox Related
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Acetamide (or acetic acid amide or ethanamide), CH3CONH2, the amide of acetic acid, is a white crystalline solid in pure form. It is produced by dehydrating ammonium acetate. It is used as a plasticizer and in the synthesis of many other organic compounds.

Acetamide is not extremely combustible, but releases irritating fumes when ignited. It is toxic by inhalation (of dust), ingestion, skin and eye contact. Skin or eye contact may cause redness and pain.

The derivative N,N-dimethylacetamide (DMA), which has two methyl groups replacing the amine protons, is used as a solvent. N-methylacetamide is often used as the simplest model in studies of the peptide bond.

Recent work on the Robert C. Byrd Green Bank Telescope has resulted in the discovery of several organic (carbon-based) compounds near the center of the Milky Way galaxy. Acetamide has been detected. This is particularly important as acetamide has an amide bond, similar to the essential bond between amino acids in proteins. This supports the theory that organic molecules that can lead to life (as we know it on Earth) can form in space.

Cancer link

Acetamide has been found to cause cancer in laboratory animals. It is classified in Group 2B "possible human carcinogen" by the IARC.

References

* cite journal
author=J. M. Hollis, F. J. Lovas, Anthony J. Remijan, P. R. Jewell, V. V. Ilyushin, and I. Kleiner
title=Detection of Acetamide (CH3CONH2): The Largest Interstellar Molecule with a Peptide Bond
journal=The Astrophysical Journal
year=2006
volume=643
issue=2
pages=L25–L28
doi=10.1086/505110

External links

*
* [http://www.mindat.org/min-13.html Mindat.org]
* [http://www.webmineral.com/data/Acetamide.shtml Webmineral.org]


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  • Acétamide — Général Nom IUPAC Acétamide Synonymes Amide de l acide acétique …   Wikipédia en Français

  • Acetamide — Ac et*am ide, n. [Acetyl + amide.] (Chem.) A white crystalline solid, from ammonia by replacement of an equivalent of hydrogen by acetyl. [1913 Webster] …   The Collaborative International Dictionary of English

  • acetamide — [as΄et am′īd, as΄ət amid; ə set′ə mīd, ə set′əmid] n. [ ACET(O) + AMIDE] colorless, soluble, organic crystals, CH3CONH2, the amide of acetic acid: used as a solvent, in lacquers and explosives, and in making organic compounds …   English World dictionary

  • acetamide — acetamidas statusas T sritis chemija formulė CH₃CONH₂ atitikmenys: angl. acetamide rus. ацетамид ryšiai: sinonimas – etanamidas …   Chemijos terminų aiškinamasis žodynas

  • acetamide — noun Etymology: International Scientific Vocabulary Date: 1869 a white crystalline amide C2H5NO of acetic acid used especially as a solvent and in organic synthesis …   New Collegiate Dictionary

  • acetamide — /euh set euh muyd , as i tam uyd/, n. Chem. a white, water soluble, crystalline solid, C2H5NO, the amide of acetic acid: used chiefly in organic synthesis. Also, acetamid /euh set euh mid, as i tam id/. Also called acetic acid amide. [1870 75;… …   Universalium

  • acetamide — noun The amide of acetic acid, CHCONH …   Wiktionary

  • acetamide — CH3CONH2; used in biomedical research. SYN: acetic amide. * * * acet·amide ə set ə .mīd, .as ət am .īd n a white crystalline amide C2H5NO of acetic acid used esp. as a solvent and in organic synthesis * * * acet·a·mide (ə setґə… …   Medical dictionary

  • acetamide — n. crystalline amide of acetic acid used mainly in organic synthesis (Chemistry) …   English contemporary dictionary

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