Paracellular transport

Paracellular transport

Paracellular transport refers to the transfer of substances "between" cells of an epithelium. [ [http://www.citracal.com/gfx/dyk_absorption.gifDiagram at citracal.com] ] [Dorlands|t_16|14158724]

It is in contrast to "transcellular transport", where the substancees travel "through" the cell, passing through both the apical membrane and basolateral membrane. [ [http://www.trinity.edu/rblyston/MicroA/Lectures/L07pt2-html/sld022.htm Epithelial Transcellular Transport ] ] [GeorgiaPhysiology|1/1ch2/s1ch2_37] [http://www.mun.ca/biology/desmid/brian/BIOL2060/CellBiol11/CB11_19.html]

The distinction is in particular significance in renal physiology. Transcellular transport is more likely to involve energy expenditure than paracellular transport. [ [http://www.acbrown.com/renal/OutTubl.htm Tubular Transport ] ]

Capillaries of Blood Brain Barrier have transcellular transport only in contrast with normal capillaries which have both - transcellular and paracellular transport. This is due to the presence of tight junctions in Blood Brain Barrier and Astrocytes that surround the capillaries.

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • paracellular transport — transport of molecules around cells and through tight junctions in an epithelial cell layer. Cf. transcellular t …   Medical dictionary

  • transport — The movement or transference of biochemical substances in biologic systems. [L. transporto, to carry over, fr. trans + porto, to carry] active t. the passage of ions or molecules across a cell membrane, not by passive diffusion but by an energy… …   Medical dictionary

  • transcellular transport — transport of molecules through the cells of an epithelial cell layer. Cf. paracellular t …   Medical dictionary

  • Magnesium transporter — This page links directly from the magnesium in biological systems page. Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from… …   Wikipedia

  • CLDN16 — Claudin 16 Identifiers Symbols CLDN16; HOMG3; PCLN1 External IDs OMIM:  …   Wikipedia

  • Плотные контакты — …   Википедия

  • Claudin — Schematische Darstellung einer Epithelzelle im Zellverband. Die Größenverhältnisse sind verzerrt, die Junctions sind eigentlich im Verhältnis viel kleiner. Die Pfeile markieren den parazellulären Weg von Molekülen über das Epithel. Claudine (lat …   Deutsch Wikipedia

  • Jonction serrée — Les jonctions serrées (ou jonctions étanches, ou encore zonula occludens) sont spécifiques des tissus épithéliaux du taxon des chordés. Elles bloquent totalement la circulation de fluides entre les cellules (voie paracellulaire) et assurent ainsi …   Wikipédia en Français

  • Tight junction — Diagram of Tight junction Latin junctio occludens Code TH …   Wikipedia

  • CLDN2 — Claudin 2, also known as CLDN2, is a human gene.cite web | title = Entrez Gene: CLDN2 claudin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=9075| accessdate = ] It belongs to the group of claudins. PBB… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”