Koplik's spots

Koplik's spots

Koplik's spots (kop'liks) are small, irregular, red spots with a minute bluish white speck in the center of each seen on the buccal mucosa and lingual mucosa (mucous membrane of the inside of the cheek and tongue) and are pathognomonic of early stage measles. They are named after Henry Koplik (1858-1927), an American pediatrician who first described them in 1896.

They often appear a few days before the rash arrives and can be a useful sign to look for in children known to be exposed to the measles virus.

The first description of these spots by some authors are ascribed to Reubold, Würzburg 1854, by others to Johann Andreas Murray (1740-1791). Before Koplik, the German internist Carl Jakob Adolf Christian Gerhardt (1833-1902) in 1874, the Danish physician N. Flindt in 1879, and the Russian Nicolai Feodorowitsch von Filatov (1847-1902) in 1897, had observed equivalent phenomena.Koplik, H. The diagnosis of the invasion of measles from a study of the exanthema as it appears on the buccal mucous membrane. Archives of Pediatrics, New York, 1896; 13: 918-922." (accessed from http://www.whonamedit.com/synd.cfm/1437.html on 9/13/2006)]


External links

* [http://www.dentistry.leeds.ac.uk/oralpath/viruses/viral%20infections/340%20images/other%20viral%20images/koplik%27s%20spots.jpgImage of Koplik's spots] - dentistry.leeds.ac.uk.

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  • Koplik's spots — Kop·lik s spots käp liks or Kop·lik spots lik n pl small bluish white dots surrounded by a reddish zone that appear on the mucous membrane of the cheeks and lips before the appearance of the skin eruption in a case of measles Koplik Henry (1858… …   Medical dictionary

  • Koplik's spots — noun small red spots with white centers found on the mucous membranes of the mouth and tongue; symptom of measles that appears one or two days before the measles rash appears • Hypernyms: ↑symptom * * * ˈkäpliks noun plural also koplik spots… …   Useful english dictionary

  • Koplik’s spots — Little spots inside the mouth that are highly characteristic of the early phase of measles (rubeola). The spots look like a tiny grains of white sand, each surrounded by a red ring. They are found especially on the inside of the cheek (the buccal …   Medical dictionary

  • Koplik's spots — /kop liks/, (in measles) small pale spots with reddish rims that appear on the lips and mucous membranes inside the cheeks before the skin eruption takes place. [1895 1900; named after Henry Koplik (1858 1927), U.S. pediatrician] * * * …   Universalium

  • Koplik's spots — small red spots with bluish white centres that often appear on the mucous membranes of the mouth in measles. [Koplik (1858–1927), US physician] …   The new mediacal dictionary

  • Koplik's spots — red spots surrounded with white areas that appear in the mouth during the early stages of measles (Medicine) …   English contemporary dictionary

  • Koplik's spots — (kop liks) Lesions of the oral cavity caused by the measles (rubeola) virus that are characterized by a bluish white speck in the center of each …   Dictionary of microbiology

  • KOPLIK, HENRY — (1858–1927), U.S. pediatrician. Koplik, who was born in New York, became assistant professor of pediatrics at Bellevue Medical College as well as consulting physician to other New York hospitals. Koplik is known as the discoverer of the… …   Encyclopedia of Judaism

  • koplik spots — noun plural see koplik s spots …   Useful english dictionary

  • Пятна Коплика (Koplik'S Spots) — небольшие красные пятна с синевато беловатой окраской в центре, которые часто появляются на слизистой оболочке полости рта у больных корью. Источник: Медицинский словарь …   Медицинские термины

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