- Lymphocytic colitis
Infobox_Disease
Name = PAGENAME
Caption =
DiseasesDB = 30087
ICD10 =
ICD9 =
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1351
MeshID = D046730Lymphocytic colitis, a subtype of
microscopic colitis , is a rare condition characterized by chronic non-bloody waterydiarrhea . Thecolonoscopy is normal but the mucosal biopsy reveals an accumulation oflymphocytes in the colonic epithelium and connective tissue (lamina propria).Collagenous colitis shares this feature but additionally shows a distinctive thickening of the subepithelial collagen table. The peak incidence of lymphocytic colitis is in persons over age 50; the disease affects women more than men.Causes
No definite etiology has been determined. Some reports have implicated long-term usage of NSAIDs,
antidepressants , and other drugs; and overactive immune responses are also suspected.Treatment
Over-the-counter antidiarrheal drugs are effective for many people with lymphocytic colitis. Anti-inflammatory drugs, such as salicylates may also help.
Corticosteroids orMesalazine s may be prescribed for people who do not respond to other drug treatment. The long-term prognosis for this disease is not clear.ee also
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Colitis
*Collagenous colitis External links
* [http://digestive.niddk.nih.gov/ddiseases/pubs/collagenouscolitis/index.htm Collagenous Colitis and Lymphocytic Colitis]
* [http://www.diseasesdatabase.com/umlsdef.asp?glngUserChoice=30087 Diseases Database]
* [http://www.gpnotebook.co.uk/simplepage.cfm?ID=1697972300 GPNotebook]
* [http://www.emedicine.com/med/topic1351.htm eMedicine.com]
* [http://www.merck.com/mmhe/print/sec09/ch126/ch126d.html Merck Manual]References
* [http://hopkins-gi.nts.jhu.edu/pages/latin/templates/index.cfm?pg=disease1&disease=29&organ=6&lang_id=1 Gasteroenterology and Hepatology Resource Center, Johns Hopkins Medical Institutes]
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