Chemotactic selection

Chemotactic selection

Chemotaxis receptors are expressed in the surface membrane with diverse dynamics, some of them have long-term characteristics as they are determined genetically, others have short-term moiety as their assembly is induced ad hoc in the presence of the ligand. The diverse feature of the chemotaxis receptors and ligands provides the possibility to select chemotactic responder cells with a simple chemotaxis assay. By chemotactic selection we can determine whether a still not characterized molecule acts via the long- or the short-term receptor pathway. Recent results proved that chemokines (e.g. IL-8, RANTES) are working on long-term chemotaxis receptors, while vasoactive peptides (e.g. endothelin) act more on the short-term ones. Term chemotactic selection is also used to design a technique which separates eukaryotic or prokaryotic cells upon their chemotactic responsiveness to selector ligands.

Chemotactic selection

References

Kohidai L and Csaba G (1988). "Chemotaxis and chemotactic selection induced with cytokines (IL-8, RANTES and TNF alpha) in the unicellular Tetrahymena pyriformis.". Cytokine 10 (7): 481–6. doi:10.1006/cyto.1997.0328. PMID 9702410. 

External links


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Chemotactic drug-targeting — A special, reversal form of drug delivery where modulation of active migratory behaviour of the target cells is used to achieve targeted effects[1]. The general components of the conjugates are designed as follows: (i) carrier – regularly… …   Wikipedia

  • Chemotaxis — is the phenomenon in which somatic cells, bacteria, and other single cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (for example, glucose) by …   Wikipedia

  • Quimiotaxis — Saltar a navegación, búsqueda La quimiotaxis es un tipo de taxis, un fenómeno en el cual las bacterias y otras células de organismos uni o multicelulares dirigen sus movimientos de acuerdo a ciertas sustancias químicas en su medio ambiente. Esto… …   Wikipedia Español

  • Selección quimiotáctica — Los receptores de quimiotaxis se expresan en la superficie de la membrana con diversas dinámicas, algunas de ellas tienen características de largo plazo, ya que están determinados genéticamente; otros tienen elementos de corto plazo por que su… …   Wikipedia Español

  • Selección quimotáctica — Este artículo está huérfano, pues pocos o ningún artículo enlazan aquí. Por favor, introduce enlaces hacia esta página desde otros artículos relaciona …   Wikipedia Español

  • Interleukin 8 — (IL 8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL 8 in their storage vesicles, the Weibel Palade bodies [Wolff B, Burns AR, Middleton J, Rot A …   Wikipedia

  • Aerotaxis — Chemotaxis (gr. chêmeia = Chemie, taxis = Ordnung, Aufmarsch) bezeichnet die Beeinflussung der Fortbewegungsrichtung von Lebewesen oder Zellen durch Stoffkonzentrationsgradienten. Wird die Bewegung in einem solchen Gradienten in Richtung auf… …   Deutsch Wikipedia

  • Chemotaxis — Übergeordnet Taxis Antwort auf chemischen Stimulus Untergeordnet positive/negative zelluläre Chemotaxis Axonlenk …   Deutsch Wikipedia

  • Chimiotactisme — Chimiotaxie La chimiotaxie, un des types de la taxie, est le phénomène par lequel les cellules corporelles, les bactéries, ainsi que les autres organismes uni , ou multicellulaires dirigent leurs mouvements en fonction de certaines espèces… …   Wikipédia en Français

  • Chimiotaxie — La chimiotaxie, l un des types de taxies, est le phénomène par lequel des cellules corporelles, des spermatozoïdes, le tube pollinique[1],[2] d un grain de pollen, ou des bactéries, ou d autres organismes uni , ou pluricellulaires se dirigent ou… …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”