Homovanillic acid

Homovanillic acid

Chembox new
ImageFile = homovanillic acid.png ImageSize = 120px
IUPACName = 2-(4-Hydroxy-3-methoxy-phenyl)acetic acid
OtherNames =
Section1 = Chembox Identifiers
CASNo = 306-08-1
PubChem = 1738
ChemSpiderID = 1675
SMILES = COC1=C(C=CC(=C1)CC(=O)O)O
MeSHName = Homovanillic+acid
Section2 = Chembox Properties
Formula = C9H10O4
MolarMass = 182.173
Appearance =
Density =
MeltingPt =
BoilingPt =
Section3 = Chembox Hazards
Solubility =
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Autoignition = Homovanillic acid (HOC6H3(OCH3)CH2COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid) is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.

In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose. cite journal |author=Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J |title=Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia |journal=Schizophr. Res. |volume=86 |issue=1-3 |pages=45–53 |year=2006 |month=September |pmid=16806836 |doi=10.1016/j.schres.2006.05.001 |url=http://linkinghub.elsevier.com/retrieve/pii/S0920-9964(06)00225-8] HVA presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma.

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  • homovanillic acid — 4 Hydroxy 3 methoxyphenylacetic acid; a phenol found in human urine; produced through the methylation of homoprotocatechuic acid on the meta OH group. It is the principal urinary metabolite of dopa and dopamine. * * * ho·mo·va·nil·lic acid və nil …   Medical dictionary

  • homovanillic acid — /hoh moh veuh nil ik, hom oh , hoh moh , hom oh /, Biochem. the end product of dopamine metabolism, C9H10O4, found in human urine. [HOMO + VANILLIC] * * * …   Universalium

  • homovanillic acid — /hoh moh veuh nil ik, hom oh , hoh moh , hom oh /, Biochem. the end product of dopamine metabolism, C9H10O4, found in human urine. [HOMO + VANILLIC] …   Useful english dictionary

  • 3,4-Dihydroxyphenylacetic acid — IUPAC name 2 (3,4 Dihydroxyphenyl)acetic acid …   Wikipedia

  • Vanillyl mandelic acid — Chembox new ImageFile = Vanilmandelic acid.svg ImageSize = IUPACName = 2 hydroxy 2 (4 hydroxy 3 methoxy phenyl)acetic acid OtherNames = Section1 = Chembox Identifiers CASNo = 55 10 7 PubChem = 1245 ChemSpiderID = 1207 SMILES = MeSHName =… …   Wikipedia

  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Анатомия эпидемии — «Анатомия эпидемии: стимуляторы, психотропные препараты и невероятный бум психических расстройств в США» (ориг.: Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America) книга Роберта… …   Википедия

  • Neuroblastoma — Neuroblastoma, NOS Classification and external resources microscopic view of a typical neuroblastoma with rosette formation ICD 10 C …   Wikipedia

  • HVA — Abbreviation for homovanillic acid. * * * hallux valgus angle; homovanillic acid * * * homovanillic acid …   Medical dictionary

  • Normetanephrine — IUPAC name 4 (2 amino 1 hydroxy ethyl) 2 methoxy phenol …   Wikipedia

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