- Vanillyl mandelic acid
ImageFile = Vanilmandelic acid.svg
IUPACName = 2-hydroxy-2-(4-hydroxy-3-methoxy-
Section1 = Chembox Identifiers
CASNo = 55-10-7
PubChem = 1245
ChemSpiderID = 1207
MeSHName = Vanilmandelic+acid
Section2 = Chembox Properties
Formula = C9H10O5
MolarMass = 198.173 g/mol
Section3 = Chembox Hazards
Vanillyl mandelic acid (VMA) is a
metaboliteof the catecholamine: norepinephrine.
VMA is found in the
urine, along with other catecholamine metabolites, including homovanillic acid(HVA). In timed urine tests the quantity ( concentrationμg /24 h) is assessed, along with creatinineclearance, and the concentration of cortisols, catecholamines, and metanephrines.
urinalysistests are used to diagnose an adrenal gland tumor called pheochromocytoma, a tumor of catecholamine-secreting chromaffincells. These tests may also be used to diagnose neuroblastomas, and to monitor treatment of these conditions.
Norepinephrine breaks down into
normetanephrineand VMA. Norepinephrine is one of the hormones produced by the adrenal glands, which are found on top of the kidneys. They are released into the blood during times of physical or emotional stress, which are factors that may skew the results of the test.
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