Germ-free animal

Germ-free animal

Germ-free animals are animals that have no microorganisms living in or on it. Such animals are raised within germ-free isolators in order to control their exposure to viral, bacterial or parasitic agents. [ University of Michigan] Germ Free Animal Facility - example facility for raising germ-free animals] When known strains of bacteria or microbiota are introduced to a germ-free animal, it is renamed as a gnotobiotic animal.

Germ-free animals are used in the study of probiotic research and other animal research requiring careful control of outside contaminants that can affect the experiment. [ Of Probiotics and Possibilities] - J. Armbrecht. Dept of Bacteriology, University of Wisconsin-Madison. August 2, 2000.]


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