Acid-citrate-dextrose

Acid-citrate-dextrose

Acid Citrate Dextrose Solution (sometimes called Anticoagulant Citrate Dextrose Solution) is a solution of citric acid, sodium citrate and dextrose in water. It is mainly used as an anticoagulant to preserve blood specimens required for tissue typing, it is also used during procedures such as plasmapheresis instead of heparin. Two different solutions (Solution A and B) are defined by the United States Pharmacopeia.

They have the following properties:

Solution A (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 20.59 to 22.75g
Dextrose (C6H12O6*H2O) 23.28g to 25.73g
Sodium (Na) 4.90g to 5.42g
Solution B (per 1000 mL)
Total Citrate (as Citric acid, anhydrous (C6H8O7)) 12.37 to 13.67g
Dextrose (C6H12O6*H2O) 13.96 to 15.44g
Sodium (Na) 2.94 to 3.25g

To make use:

A B
Citric Acid, anhydrous (C6H8O7) 7.3g 4.4
Sodium Citrate, dihydrate 22.0g 13.2
Dextrose, monohydrate (C6H12O6*H2O) 24.5g 14.7
Water for Injection to make 1000 mL 1000 mL

Dissolve the ingredients and mix. Filter until clear.

References

United States Pharmacopeia 26, 2002, pp 158.

External links


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Acid-Citrate-Dextrose — Acid Citrate Dextrose, ACD (oder auch: ACD Stabilisator), ist eine Lösung von Zitronensäure, Natriumcitrat und D Glucose in Wasser, und wurde 1943 von Loutit et al. konzipiert. Sein pH Wert liegt bei 5,0. Nach Vermischen mit Blut beträgt der pH… …   Deutsch Wikipedia

  • acid citrate dextrose — (ACD) anticoagulant citrate dextrose solution …   Medical dictionary

  • acid citrate dextrose solution — anticoagulant citrate dextrose s …   Medical dictionary

  • acid-citrate-dextrose — Citric acid/sodium citrate buffered glucose solution used as an anticoagulant for blood (citrate complexes calcium) …   Dictionary of molecular biology

  • acid-citrate-dextrose — A citrate anticoagulant used for the collection and preservation of whole blood. It has largely been replaced by newer anticoagulants (CPD, Adsol) that allow for longer shelf life for blood and blood products …   Medical dictionary

  • anticoagulant citrate dextrose solution — [USP] a solution of citric acid, sodium citrate, and dextrose in water for injection, used as an anticoagulant in the preservation of whole blood …   Medical dictionary

  • anticoagulant citrate phosphate dextrose solution — [USP] a solution containing citric acid, sodium citrate, monobasic sodium phosphate, and dextrose in water for injection; used for preservation of whole blood or red cells for up to 21 days. Called also citrate phosphate dextrose s. and CPD s …   Medical dictionary

  • ACD — Abbreviation for acid citrate dextrose. * * * absolute cardiac dullness; absolute claudication distance; acid citrate dextrose [solution]; actinomycin D; active compression decompression; adult celiac disease; advanced care directive; allergic… …   Medical dictionary

  • Blood transfusion — Intervention Plastic bag containing packed red blood cells in citrate, phosphate, dextrose, and adenine (CPDA) solution …   Wikipedia

  • Abkürzungen in der Medizin — Dies ist eine Liste der Abkürzungen und Akronyme, wie sie in der Medizin verwendet werden. Die Abkürzungen kommen neben der Klinik mit ihren vielfältigen Fachdisziplinen aus den Bereichen Biochemie, Physiologie und Laboratoriumsmedizin. Auch die… …   Deutsch Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”