- C4BP (protein)
protein
Name = complement component 4 binding protein, alpha
caption =
width =
HGNCid = 1325
Symbol = C4BPA
AltSymbols = C4BP
EntrezGene = 722
OMIM = 120830
RefSeq = NM_000715
UniProt = P04003
PDB =
ECnumber =
Chromosome = 1
Arm = q
Band = 32
LocusSupplementaryData = protein
Name = complement component 4 binding protein, beta
caption =
width =
HGNCid = 1328
Symbol = C4BPB
AltSymbols = C4BP
EntrezGene = 725
OMIM = 120831
RefSeq = NM_000716
UniProt = P20851
PDB =
ECnumber =
Chromosome = 1
Arm = q
Band = 32
LocusSupplementaryData =C4BP is a protein involved in the
complement system . C4BP has a hydra-like structure with a central stalk and seven branching alpha-chains.Functions
It inhibits the action of C4. It splits
C4 convertase and is a cofactor for factor I which cleaves C4b.C4BP binds necrotic cells and DNA, to clean up after swelling.
It also binds
CD40 onB cells which potentiaties proliferation and costimulation.External links
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