Iron overload disorder

Iron overload disorder

SignSymptom infobox
Name = PAGENAME


Caption =
DiseasesDB = 5581
ICD10 = ICD10|R|79|0|r|70
ICD9 = ICD9|790.6
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D019190
In medicine, iron overload disorders are diseases caused by the accumulation of iron in the body. Organs commonly affected are the liver, heart and endocrine glands. [cite journal |author=Andrews NC |title=Disorders of iron metabolism |journal=N. Engl. J. Med. |volume=341 |issue=26 |pages=1986–95 |year=1999 |pmid=10607817|doi= 10.1056/NEJM199912233412607]

Causes

The causes can be distinguished between primary (generally genetic) and secondary (due to other conditions). [cite journal |author=Pietrangelo A |title=Haemochromatosis |journal=Gut |volume=52 Suppl 2 |issue= |pages=ii23–30 |year=2003 |pmid=12651879 |doi= |url=http://gut.bmjjournals.com/cgi/content/abstract/52/suppl_2/ii23]

Primary iron overload

Secondary iron overload

* Dietary iron overload
* Transfusional iron overload
* Long term haemodialysis
* Chronic liver disease
** Hepatitis C
** Alcoholic cirrhosis, especially when advanced
** Non-alcoholic steatohepatitis
* Porphyria cutanea tarda
* Post-portacaval shunting
* Dysmetabolic iron overload syndrome

Miscellaneous

The part-genetic, part-environmental syndrome known as African iron overload in sub-Sahara Africa (OMIM|601195)

ee also

* Iron deficiency
* Siderosis
* Hemosiderosis
* Human iron metabolism

References

External links

* [http://medic.med.uth.tmc.edu/ptnt/00001041.htm Texas Medical Center]
* [http://www.merck.com/mrkshared/mmanual/section11/chapter128/128a.jsp Merck]
* [http://www.ironoverload.org/ Iron Overload.org]


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