Second-generation antidepressants

Second-generation antidepressants

The Second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction (approximately coinciding with the 1970s and 1980s), rather than by their chemical structure or by their pharmacological effect. As a consequence, there is some controversy over which treatments actually belong in this class.

The term "Third generation antidepressant" is sometimes used to refer to even newer antidepressants,cite journal |author=Olver JS, Burrows GD, Norman TR |title=Third-generation antidepressants: do they offer advantages over the SSRIs? |journal=CNS Drugs |volume=15 |issue=12 |pages=941–54 |year=2001 |pmid=11735614 |doi= |url=] often selective serotonin reuptake inhibitors, such as fluoxetine, reboxetine, mirtazapine, nefazodone, paroxetine, sertraline, and venlafaxine. However, this usage is not universal.

Examples

This list is not exhaustive, and different sources vary upon which items should be considered second-generation.

* amoxapine
* bupropion
* maprotiline
* mianserin
* nomifensine
* trazodone

References

External links

*
* [http://www.toxlab.co.uk/tca2nd.htm#Second%20Generation Diagrams at toxlab.co.uk]
* [http://jcp.sagepub.com/cgi/content/abstract/25/4/241 Overview at sagepub.com]
* [http://psyweb.com/Glossary/sga.jsp Overview at psyweb.com]
* [http://www.sciencedaily.com/releases/2005/09/050920081731.htm Overview at sciencedaily.com]
* [http://sabryabdelfattah.tripod.com/docs/ANTIDPRS.htm Overview at sabryabdelfattah.tripod.com]


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Imipramine and the Tricyclic Antidepressants —    (from 1957)    By the mid 1950s, a number of drugs had become available with some effectiveness in nonhospital depression, such as meprobamate (Carter Wallace’s Miltown, launched in 1955) or the amphetamines (see ANTIDEPRESSANT: first… …   Historical dictionary of Psychiatry

  • Discovery and development of dual serotonin and norepinephrine reuptake inhibitors — Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs used in the treatment of major depressive disorder (MDD). SNRIs are potent inhibitors of serotonin (5 Hydroxytryptamine, 5 HT) and norepinephrine (NE,… …   Wikipedia

  • Sertraline — Lustral redirects here. For the electronic music band, see Lustral (band). Sertraline Systemat …   Wikipedia

  • Nefazodone — Systematic (IUPAC) name 1 (3 [4 (3 chlorophenyl)piperazin 1 yl]propyl) 3 ethyl 4 (2 phenoxyethyl) 1H 1,2,4 triazol 5(4H) one Clinical data AHFS …   Wikipedia

  • Paroxetine — Systematic (IUPAC) name …   Wikipedia

  • Antidepressant —    The concept of drugs thought to work specifically against a disease called depression is probably a misnomer because depression often includes anxiety and other symptoms as well. Yet, antidepressant has claimed a firm place in the nomenclature …   Historical dictionary of Psychiatry

  • Fluoxetine — Prozac redirects here. For other uses, see Prozac (disambiguation). Fluoxetine Systematic (I …   Wikipedia

  • Escitalopram — The Cipralex brand name should not be confused with the antibiotic drug ciprofloxacin or its various brand names such as Cipro. Escitalopram …   Wikipedia

  • Moclobemide — Systematic (IUPAC) name 4 chloro N (2 morpholin 4 ylethyl)benzamide Clinical data Trade names Aurorix …   Wikipedia

  • Fluoxétine — « Prozac » redirige ici. Pour la série télévisée québécoise, voir Prozac : La maladie du bonheur. Fluoxétine …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”