Immunoglobulin fold

Immunoglobulin fold

An immunoglobulin fold is a common all-β protein fold that consists of a 2-layer sandwich of ~7 antiparallel β-strands arranged in two β-sheets.

The backbone switches repeatedly between the two β-sheets. Typically, the pattern is (N-terminal β-hairpin in sheet 1)-(β-hairpin in sheet 2)-(β-strand in sheet 1)-(C-terminal β-hairpin in sheet 2). The cross-overs between sheets form an "X", so that the N- and C-terminal hairpins are facing each other.

External links

* [http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.c.b.html SCOP listing of immunoglobulin domains of known structure]


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Immunoglobulin superfamily — The immunoglobulin superfamily (IgSF) is a large group of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared… …   Wikipedia

  • Rossmann fold — An example of the Rossmann fold, a structural domain of a decarboxylase protein from the bacterium Staphylococcus epidermidis (PDB ID 1G5Q) with the bound flavin mononucleotide cofactor shown. The Rossmann fold is a protein structural motif found …   Wikipedia

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • DNA-binding domain — A DNA binding domain (DBD) is an independently folded protein domain that contains at least one motif that recognizes double or single stranded DNA. A DBD can recognize a specific DNA sequence (a recognition sequence) or have a general affinity… …   Wikipedia

  • Beta sheet — The β sheet (also β pleated sheet) is the second form of regular secondary structure in proteins consisting of beta strands connected laterally by three or more hydrogen bonds, forming a generally twisted, pleated sheet (the most common form of… …   Wikipedia

  • Major sperm protein — MSP Structure of MSP dimer from A. suum. The β sheets are shown in orange Identifiers Symbol Major Sperm Protein, MSP Entrez …   Wikipedia

  • Гельфанд, Израиль Моисеевич — В Википедии есть статьи о других людях с такой фамилией, см. Гельфанд. Израиль Моисеевич Гельфанд Дата рождения: 20  …   Википедия

  • Израиль Гельфанд — Израиль Моисеевич Гельфанд Дата рождения: 2 сентября 1913 Место рождения: Окны Тираспольского уезда Херсонской губернии Гражданство: СССР, США Научная сфера: математика, биология, педагогика Альма матер: МГУ …   Википедия

  • Израиль Моисеевич Гельфанд — Дата рождения: 2 сентября 1913 Место рождения: Окны Тираспольского уезда Херсонской губернии Гражданство: СССР, США Научная сфера: математика, биология, педагогика Альма матер: МГУ …   Википедия

  • All-β proteins — An all β proteins is a class of structural domains in which the secondary structure is composed entirely of β sheets, with the possible exception of a few isolated α helices on the periphery.Common examples include the SH3 domain, the beta… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”