Proto-mitochondrion

Proto-mitochondrion

Taxobox
color = lightgrey
name = Proto-mitochondrion
regnum = Bacteria
phylum = Proteobacteria
classis = Alpha Proteobacteria

The proto-mitochondrion is the ancestral bacterial endosymbiont from which all mitochondriaare thought to be derived.

Phylogeny

The phylogenetic analyses of the few genes that are still encoded in the genomes of modern mitochondria suggest an alpha-proteobacterial nature for this endosymbiont. Although the order "Rickettsiales" has been proposed as the alpha-proteobacterial sister-group of mitochondria, there is no definitive evidence as to from which alpha-proteobacterial group the proto-mitochondrion emerged.

Metabolism

Toni Gabaldón and Martijn Huynen (2003) reconstructed the proteome and corresponding metabolism of the proto-mitochondrion by comparingextant alpha-proteobacterial and eukaryotic genomes. They concluded that this organism was an aerobic alpha-proteobacterium catabolyzing lipids, glycerol and other compounds provided by the host. At least 630 gene families derived from this organism can still be found in the 9 eukaryotic genomes analyzed in the study.

References

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