Veratridine

Veratridine

Chembox new
ImageFile = ALX-550-307.png ImageSize = 250px
IUPACName =
OtherNames = Veratrine
3-Veratroylveracevine
Section1 = Chembox Identifiers
CASNo = 71-62-5
PubChem = 6280
SMILES = C [C@H] 1CC [C@H] 2 [C@@] ( [C@] 3( [C@H] (C [C@] 4 ( [C@@H] 5CC [C@H] 6 [C@] 7( [C@] 5(C [C@] 4 ( [C@@H] 3CN2C1)O)O [C@@] 6( [C@H] (CC7)OC(=O) C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
Section2 = Chembox Properties
Formula = C36H51NO11
MolarMass = 673.79 g/mol
Appearance =
Density =
MeltingPt =
BoilingPt =
Solubility =
Section3 = Chembox Hazards
MainHazards =
FlashPt =
Autoignition =

Veratridine is a steroid-derived alkaloid from the family of Liliaceae that functions as a neurotoxin by activating sodium ion channels. It is primarily obtained from the herb hellebore (veratrum) and sabadilla seeds. It binds to intramembrane receptor site 2 and increasing intracellular Ca2+ concentration. It acts by preferentially binding to activated Na+ channels causing persistent activation.

It is used in ointments for the treatment of neuralgia and rheumatoid pain.fact


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  • veratridine — [və rat′rə dēn΄, və rat′rədin] n. [< L veratrum, hellebore (see VERATRINE) + ID(E) + INE3] an irritating, poisonous amorphous alkaloid, C36H51NO11, found in sabadilla seeds …   English World dictionary

  • veratridine — noun Etymology: veratrine + idine Date: 1907 a poisonous alkaloid C36H51NO11 occurring especially in sabadilla seed …   New Collegiate Dictionary

  • veratridine — /veuh ra tri deen , din/, n. Chem. a yellowish white, amorphous, water soluble, poisonous alkaloid, C36H51NO11, occurring with veratrine in the seeds of the sabadilla. [1905 10; < L veratr(um) hellebore + ID3 + INE2] * * * …   Universalium

  • veratridine — noun Any of a family of neurotoxic steroid derived alkaloids, occurring in the seeds of the sabadilla plant See Also: veratrine …   Wiktionary

  • veratridine — An alkaloid derived from Veratrum viridae and V. album. Probably responsible for antihypertensive properties of this class of alkaloids. * * * ve·rat·ri·dine və ra trə .dēn n a poisonous amorphous alkaloid C36H51NO11 occurring esp. in sabadilla… …   Medical dictionary

  • veratridine — ve·rat·ri·dine …   English syllables

  • veratridine — /vəˈrætrədin/ (say vuh ratruhdeen) noun a soluble amorphous alkaloid, C36H51NO11, occurring with veratrine in the seeds of the sabadilla. Also, veratridin /vəˈrætrədən/ (say vuh ratruhduhn). {veratr(ine) + id(e) + ine2} …  

  • veratridine — rəˌdēn, də̇n noun ( s) Etymology: veratr + idine : a poisonous amorphous alkaloid C36H51NO11 occurring in sabadilla seed and in some hellebores (as American hellebore) * * * /veuh ra tri deen , din/, n. Chem. a yellowish white, amorphous, water… …   Useful english dictionary

  • ver|a|trine — «VEHR uh treen, trihn», noun. 1. a poisonous mixture containing veratridine and other alkaloids extracted from the seeds of the sabadilla, used medicinally as an ointment, especially for the relief of rheumatism and neuralgia. 2. = veratridine… …   Useful english dictionary

  • ve|rat|ri|din — «vuh RAT ruh dihn», noun. = veratridine. (Cf. ↑veratridine) …   Useful english dictionary

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