Active chromatin sequence
- Active chromatin sequence
An active chromatin sequence (ACS) is a region of DNA in a eukaryotic chromosome in which histone modifications such as acetylation lead to exposure of the DNA sequence thus allowing binding of transcription factors and transcription to take place. ACSs may occur in non-expressed gene regions which are assumed to be "poised" for transcription.
ee also
Chromatin
References
# [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15070753| Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries]
Wikimedia Foundation.
2010.
Look at other dictionaries:
Chromatin immunoprecipitation — The procedure of chromatin immunoprecipitation (ChIP) assay and methods of analysis Chromatin Immunoprecipitation (ChIP) is a type of immunoprecipitation experimental technique used to investigate the interaction between proteins and DNA in the… … Wikipedia
Chromatin — The major structures in DNA compaction; DNA, the nucleosome, the 10nm beads on a string fibre, the 30nm fibre and the metaphase chromosome Chromatin is the combination of DNA and proteins that make up the contents of the nucleus of a cell. The… … Wikipedia
cell — cell1 cell like, adj. /sel/, n. 1. a small room, as in a convent or prison. 2. any of various small compartments or bounded areas forming part of a whole. 3. a small group acting as a unit within a larger organization: a local cell of the… … Universalium
Long non-coding RNA — Long noncoding RNAs (long ncRNAs) are generally considered (somewhat arbitrarily) as non protein coding transcripts longer than 200 nucleotides. This limit is due to practical considerations including the separation of RNAs in common experimental … Wikipedia
PAXIP1 — PAX interacting (with transcription activation domain) protein 1 Identifiers Symbols PAXIP1; CAGF29; FLJ41049; PACIP1; PAXIP1L; PTIP; TNRC2 External IDs … Wikipedia
PAX2 — Paired box 2 PDB rendering based on 1k78 … Wikipedia
Chemical biology — is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems.… … Wikipedia
Nucleosome — Nucleosomes are the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound around a histone protein core.[1] This structure is often compared to thread wrapped around a spool.[2] Nucleosomes form the fundamental repeating … Wikipedia
Epigenetics — In biology, the term epigenetics refers to changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. These changes may remain through cell divisions for the remainder of the cell s life and may also last… … Wikipedia
DNA methylation — Illustration of a DNA molecule that is methylated at the two center cytosines. DNA methylation plays an important role for epigenetic gene regulation in development and disease. DNA methylation is a biochemical process that is important for… … Wikipedia
