MDL Chime

MDL Chime

MDL "Chime" is a free plugin used by web browsers to display the three dimensional structures of molecules. It is part of the ISIS product line acquired by Symyx Technologies from scientific publisher Elsevier in October 2007. It is based on the RasMol code.

Chime is used by a wide range of biochemistry web sites for the visualization of macromolecules. Many of these sites are linked to the "World Index of Molecular Visualization Resources" [http://molvisindex.org MolVisIndex.Org] . Chime was also used until 2006 at the Protein Data Bank to examine structures stored there.

Although available in 1998 in both Windows 98 and Mac OS 9 versions for both Netscape and Internet Explorer browsers, development of Chime did not follow the move to Mac OS X for the Mac and support for Windows-based browsers other than Internet Explorer was dropped (although it works well in Mozilla Firefox). No significant features have been added since 1998 except for updates in the installation package to follow the development of Windows and Internet Explorer.

Chime may be superseded by Jmol, but the current market share and trends are unclear. Jmol is a non-proprietary Java molecular visualization application/applet that has maintained most Chime command compatibility while adding features.

Two features of Chime which are not yet reproduced with Jmol:

*'Sculpt' mode: The ability to change the conformation of molecules in a realistic way by dragging their atoms to new positions. This is a useful feature for exploring the conformational possibilities of a molecule such as the inability to rotate a carbon-carbon double bond.

*Calculating and drawing molecular surfaces coloured according to electrostatic or hydrophobic potential. Chime can calculate these surfaces for any molecule.

External links

* [http://www.mdl.com/products/framework/chime/ Symyx: MDL Chime]
* [http://www.rcsb.org/pdb/index.html RCSB Protein Data Bank]
* [http://molviz.org MolviZ.Org: Molecular Visualization Resources] with rich collection of molecules
* [http://webpages.dcu.ie/~pratta/ Dublin City University CHIME and Jmol Pages]


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • MDL Information Systems — MDL Information Systems, a provider of R D informatics offerings for the life sciences and chemicals industries and acquired by Symyx Technologies, Inc. in 2007, was launched as a computer aided drug design firm (originally named Molecular Design …   Wikipedia

  • Chime — Contents 1 Musical instrument or tone 2 Popular culture 3 Other 4 …   Wikipedia

  • Carbohydrate — Carbohydrates (from hydrates of carbon ) or saccharides (Greek σάκχαρον meaning sugar ) are the most abundant of the four major classes of biomolecules, which also include proteins, lipids and nucleic acids. They fill numerous roles in living… …   Wikipedia

  • Coenzyme Q - cytochrome c reductase — The coenzyme Q : cytochrome c oxidoreductase, sometimes called the cytochrome bc 1 complex, and at other times complex III, is the third complex in the electron transport chain (EC number|1.10.2.2), playing a critical role in biochemical… …   Wikipedia

  • List of Dublin City University faculties, schools, research centres and laboratories — This list of Dublin City University faculties, schools, research centres and laboratories covers the university s diverse and interdisciplinary research interest.: Note: this list is incomplete. Faculties and Schools*… …   Wikipedia

  • Hemoglobin — Hemoglobin, human, adult (heterotetramer, (αβ)2) Structure of human hemoglobin. The protein s α and β subunits are in red and blue, and the iron containing heme groups in green. Fro …   Wikipedia

  • Cytochrome c oxidase — The crystal structure of bovine cytochrome c oxidase in a phospholipid bilayer. The intermembrane space lies to top of the image. Adapted from PDB 1OCC (It is a ho …   Wikipedia

  • NADH dehydrogenase — Structure of NADH dehydrogenase Identifiers EC number 1.6.5.3 …   Wikipedia

  • Protein Data Bank — The Protein Data Bank (PDB) is a repository for 3 D structural data of proteins and nucleic acids. These data, typically obtained by X ray crystallography or NMR spectroscopy and submitted by biologists and biochemists from around the world, are… …   Wikipedia

  • Isis (disambiguation) — Isis was a goddess in Egyptian mythology.Isis may also refer to:Geography* The Isis, a segment of the River Thames * Isis Highway, an Australian highway * Shire of Isis, an area in Queensland, AustraliaMusic* Isis (band), an American post metal… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”