U5

U5 or U-5 may refer to:

* The IATA designator code for USA3000 Airlines
* "U-5", a subway line on the Munich_U-Bahn in Germany
* U5 (Berlin U-Bahn), a subway line in Berlin, Germany
* German submarine "U-5", one of several German submarines
* U5, an unemployment figure released by the United States Bureau of Labor Statistics