Ovalocytosis

Ovalocytosis

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 29071
ICD10 = ICD10|D|58|1|d|55
ICD9 = ICD9|282.1
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D004612

Ovalocytosis is an inherited condition in which a person's red blood cells, which are supposed to be round, instead have a slightly oval or elliptical shape (also known as hereditary elliptocytosis). This condition is associated with mild hemolytic anemia. In severe cases, the disease may be treated by removal of the spleen.

The term 'ovalocytosis' is most commonly used in reference to a particular subtype of hereditary elliptocytosis known as South-East Asian ovalocytosis, which is caused by a particular mutation in Band 3, an erythrocyte membrane protein.

South-East Asian ovalocytosis is common in some communities in Malaysia and Papua New Guinea, as it confers some resistance to cerebral Falciparum Malaria.cite web |url=http://www.ajtmh.org/cgi/reprint/60/6/1056 |title=Prevention of cerebral malaria in children in Papua New Guinea by southeast Asian ovalocytosis band 3 -- Allen et al. 60 (6): 1056 -- American Journal of Tropical Medicine and Hygiene |accessdate=2008-02-26 |format= |work=]

ee also

Hereditary elliptocytosis

References


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Look at other dictionaries:

  • ovalocytosis — Hereditary disorder of erythrocytes relatively common in areas where malaria is endemic. Not only are the erythrocytes more rigid, but there is a mutation in band III, the anion transporter …   Dictionary of molecular biology

  • ovalocytosis — SYN: elliptocytosis. * * * ovalo·cy·to·sis .sī tō səs n, pl to·ses .sēz ELLIPTOCYTOSIS * * * ovalo·cy·to·sis (o val″o si toґsis) elliptocytosis …   Medical dictionary

  • ovalocytosis — ovalo·cy·to·sis …   English syllables

  • ovalocytosis — …   Useful english dictionary

  • Southeast Asian ovalocytosis — Classification and external resources ICD 9 282.1 OMIM 109270 MeSH …   Wikipedia

  • овалоцитоз — (ovalocytosis; овалоцит + оз; син. эллиптоцитоз) наличие в крови значительного количества овалоцитов, напр. при овалоцитарной гемолитической анемии …   Большой медицинский словарь

  • Овалоцито́з — (ovalocytosis: Овалоцит + оз; син. эллиптоцитоз) наличие в крови значительного количества овалоцитов, например при овалоцитарной гемолитической анемии …   Медицинская энциклопедия

  • Hereditary elliptocytosis — Classification and external resources Blood smear showing elliptocytes ICD 10 D …   Wikipedia

  • Duffy antigen system — Duffy blood group, chemokine receptor Identifiers Symbols DARC; CCBP1; CD234; Dfy; FY; GPD External IDs …   Wikipedia

  • Band 3 — Solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) Atomic microscope image of Band 3 …   Wikipedia

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