- Hyperaldosteronism
Hyperaldosteronism, also aldosteronism, is a
medical condition where too muchaldosterone is produced by theadrenal glands , which can lead to lowered levels ofpotassium in theblood .Types
*: Primary hyperaldosteronism, often caused by an adrenal cortical adenoma (a tumor), is also known as
Conn's syndrome .*: Secondary hyperaldosteronism is due to overactivity of the
renin-angiotensin system .In
endocrinology , the terms "primary" and "secondary" are used to describe the abnormality (e.g. elevated aldosterone) in relation to the defect, i.e. the tumor's location. The adjective "primary" refers to an abnormality that directly leads to pathology, i.e. aldosteronism is caused by the apparatus that generates aldosterone. "Secondary" refers to an abnormality that indirectly results in pathology through a predictable physiologic pathway, i.e. arenin producing tumor leads to increased aldosterone, as the body's aldosterone production is normally regulated by renin levels.ymptoms
It can be
asymptomatic , but the following symptoms can be present* Fatigue
*Headache
*High blood pressure
*Hypokalemia
* Intermittent or temporaryparalysis
*Muscle spasms
*Muscle weakness
*Numbness
*Polyuria
*Polydipsia
* Tingling
*Hypernatraemia
*Metabolic alkalosis ee also
*
Hypoaldosteronism Treatment
Treatment includes
Spironolactone ,a K+ sparing diuretic that works by acting as an aldosterone antagonistExternal links
* [http://www.merck.com/mmhe/sec13/ch164/ch164e.html Merck Manual]
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