- Slow virus
A slow virus is a
virus , or a viruslike agent, etiologically associated with adisease having a long incubation period of months to years with a gradual onset frequently terminating in severe illness and/or death.A slow virus disease is a disease that follows a slow, progressive course spanning months to years, frequently involving thecentral nervous system and ultimately leading to death; examples are visna and maedi of sheep, caused by viruses of thegenus Lentivirus (familyRetroviridae ), andsubacute sclerosing panencephalitis , apparently caused by themeasles virus .
Transmissible spongiform encephalopathies (TSEs), includingCreutzfeldt-Jakob disease of humans,scrapie of sheep, andbovine spongiform encephalopathy (BSE) of cattle may also be classified under slow virus disease but are now considered to beprion diseases.Characteristics of Slow virus diseases are:They have long incubation periods ranging from months to years.They have slow but relentless progressive courses terminating fatally. They have a genetic pre-disposition.The immune system does not seem to play a role in its protection.ee also
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Clinical latency
*Virus latency
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