FNIR

fNIR stands for functional near-infrared imaging. fNIR is a spectroscopic neuro-imaging method for measuring the level of neuronal activity in the brain. The method is based on neuro-vascular coupling, that is, the relationship between metabolic activity and oxygen level (oxygenated hemoglobin) in feeding blood vessels.

There are three types of fNIR:

*CW - continuous wave - In this method, infrared light shines at the same intensity level during the measurement period. The detected signal is lower intensity static signal (dc valued)

*FD - frequency domain - In this method, input signal is modulated sinusoid at some frequency and detected output signal has changes in amplitude and phase.

*TR - time resolved - In time resolve spectroscopy, a very short pulse is introduced to measured and the pulse length is usually on the order of picoseconds. The detected signal is usually a longer signal and has a decay time.

*fNIR device was first invented by Dr. Britton Chance of the University of Pennsylvania. Current cwFNIR devices have improved with the advent of electronics. [http://www.redorbit.com/news/health/107194/athome_breast_cancer_detector_tested/index.html] At the Optical Brain Imaging Lab of Drexel University, in collaboration with Penn, battery operated, wireless cwfNIR devices have been developed. [http://www.newswise.com/articles/view/518934/]

External links

* [http://www.uphs.upenn.edu/biocbiop/faculty/pages/chance.html Lab of BC at University of Pennsylvania]
* [http://www.biomed.drexel.edu/fnir/ Optical Brain Imaging Lab at Drexel University]

See also

*Near infrared spectroscopy