Tocopheryl acetate

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ImageFile = Tocopheryl acetate.png ImageSize = 250px
IUPACName = [(2R)-2,5,7,8-Tetramethyl-2- [(4R,8R)-4,8,12-trimethyltridecyl] chroman-6-yl] acetate
OtherNames = Tocopherol acetate
Vitamin E acetate
Section1 = Chembox Identifiers
CASNo = 58-95-7
PubChem = 86472
SMILES = CC1=C2C(O [C@@] (CCC [C@H] (C)CCC [C@H] (C)CCCC(C)C)(C)CC2)=C(C)C(C)=C1OC(C)=O
Section2 = Chembox Properties
Formula = C₃₁H₅₂O₃
MolarMass = 472.743 g/mol
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Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C₃₁H₅₂O₃ (for 'α' form). It is the ester of acetic acid and tocopherol (vitamin E). It is often used in dermatological products such as skin creams.

Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product. It is believed that the acetate is slowly hydrolyzed once it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays. [cite journal |author=Beijersbergen van Henegouwen G, Junginger H, de Vries H |title=Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat) |journal=J Photochem Photobiol B |volume=29 |issue=1 |pages=45–51 |year=1995 |pmid=7472802 |doi=10.1016/1011-1344(95)90251-1]

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