Matteo Carandini

Matteo Carandini
Matteo Carandini
Born 1967
Rome, Italy
Residence London, England
Nationality Italian, American
Fields Neuroscience (Visual Neuroscience, Computational Neuroscience, Systems Neuroscience)
Institutions University College London (professor)
Notable awards McKnight Scholar 2005, GlaxoSmithKline / Fight for Sight Chair 2007, European Research Council Advanced Investigator 2009, Wellcome Trust Senior Investigator, 2011

Matteo Carandini (born 1967) is a contemporary neuroscientist who studies the visual system. He received a PhD in Neural Science from New York University and continued as a postdoctoral fellow at Northwestern University. After holding positions in Zurich (1999–2002) and in San Francisco (2002–2008), he is currently a Professor at University College London.

His studies focus on the lateral geniculate nucleus and on the visual cortex (V1). In the 1990s, working with David Heeger and J Anthony Movshon he refined and provided evidence for Heeger's normalization model of V1 responses.[1][2]

Together with David Ferster he characterized the relationship between synaptic excitation, synaptic inhibition, membrane potential, and firing rate in visual cortex [3][4] and discovered that prolonged visual stimulation causes a tonic hyperpolarization in V1 neurons.[5]

More recent work concerns the characterization of fast adaptive mechanisms in the responses of the early visual system,[6][7] a comparison with the properties of natural images [8] and a test of the resulting models in the responses to complex natural stimuli.[9]

External links

References

  1. ^ Carandini, M; Heeger, DJ (1994). "Summation and division by neurons in primate visual cortex". Science 264 (5163): 1333–6. Bibcode 1994Sci...264.1333C. doi:10.1126/science.8191289. PMID 8191289.  edit
  2. ^ Carandini, M; Heeger, DJ; Movshon, JA (1997). "Linearity and normalization in simple cells of the macaque primary visual cortex". Journal of Neuroscience 17 (21): 8621–44. PMID 9334433.  edit
  3. ^ Anderson, JS; Carandini, M; Ferster, D (2000). "Orientation tuning of input conductance, excitation, and inhibition in cat primary visual cortex". Journal of neurophysiology 84 (2): 909–26. PMID 10938316.  edit
  4. ^ Carandini, M; Ferster, D (2000). "Membrane potential and firing rate in cat primary visual cortex". Journal of Neuroscience 20 (1): 470–84. PMID 10627623.  edit
  5. ^ Carandini, M; Ferster, D (1997). "A tonic hyperpolarization underlying contrast adaptation in cat visual cortex". Science 276 (5314): 949–52. doi:10.1126/science.276.5314.949. PMID 9139658.  edit
  6. ^ Bonin, V.; Mante, V.; Carandini, M. (2005). "The Suppressive Field of Neurons in Lateral Geniculate Nucleus". Journal of Neuroscience 25 (47): 10844. doi:10.1523/JNEUROSCI.3562-05.2005. PMID 16306397.  edit
  7. ^ Carandini, M.; Demb, J. B.; Mante, V.; Tolhurst, D. J.; Dan, Y.; Olshausen, B. A.; Gallant, J. L.; Rust, N. C. (2005). "Do We Know What the Early Visual System Does?". Journal of Neuroscience 25 (46): 10577–10597. doi:10.1523/JNEUROSCI.3726-05.2005. PMID 16291931.  edit
  8. ^ Mante, V.; Frazor, R. A.; Bonin, V.; Geisler, W. S.; Carandini, M. (2005). "Independence of luminance and contrast in natural scenes and in the early visual system". Nature Neuroscience 8 (12): 1690. doi:10.1038/nn1556. PMID 16286933.  edit
  9. ^ Mante, V.; Bonin, V.; Carandini, M. (2008). "Functional Mechanisms Shaping Lateral Geniculate Responses to Artificial and Natural Stimuli". Neuron 58 (4): 625. doi:10.1016/j.neuron.2008.03.011. PMID 18498742.  edit



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