- Ophiorrhiza
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Ophiorrhiza 
Ophiorrhiza mungos Scientific classification Kingdom: Plantae (unranked): Angiosperms (unranked): Eudicots (unranked): Asterids Order: Gentianales Family: Rubiaceae Genus: Ophiorrhiza
L.Species About 150,[1] see text
Ophiorrhiza is a genus of flowering plants in the Rubiaceae|coffee family. Species of the genus contain camptothecin, an alkaloid used to make chemotherapeutic agents.[2][3] So many of Ophiorrhiza species are endemic to certain areas of western Ghats. Species include:
- Ophiorrhiza acuminata[4]
- Ophiorrhiza blumeana[5]
- Ophiorrhiza bracteata[5]
- Ophiorrhiza cantoniensis
- Ophiorrhiza carinata
- Ophiorrhiza caudata[2]
- Ophiorrhiza dulongensis
- Ophiorrhiza filistipula
- Ophiorrhiza japonica
- Ophiorrhiza kuroiwai[6]
- Ophiorrhiza liukiuensis[4]
- Ophiorrhiza lurida
- Ophiorrhiza major[5]
- Ophiorrhiza michelloides[7]
- Ophiorrhiza mungos
- Ophiorrhiza nutans
- Ophiorrhiza prostrata[1]
- Ophiorrhiza pumila[4]
- Ophiorrhiza rosea
- Ophiorrhiza rugosa
- Ophiorrhiza succirubra
References
- ^ a b Beegum, A. S., et al. (2007). Organogenesis from leaf and internode explants of Ophiorrhiza prostrata, an anticancer drug (camptothecin) producing plant. Electronic Journal of Biotechnology 10:1.
- ^ a b Joseph, G. and J. P. Joseph. Rediscovery of Ophiorrhiza caudata (Rubiaceae) from the Western Ghats of Kerala. Rheedia 19 45.
- ^ Viraporn, V., et al. (2010). Correlation of camptothecin-producing ability and phylogenetic relationship in the genus Ophiorrhiza. Planta Med. in pub.
- ^ a b c Sirikantaramas, S., et al. (2008). Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants. PNAS 105:18 6782.
- ^ a b c Arbain, D, et al. (1998). Unusual indole alkaloids from Ophiorrhiza blumeana Korth. J. Chem. Soc., Perkin Trans 1.
- ^ Asano, T., et al. (2004). Camptothecin production by in vitro cultures of Ophiorrhiza liukiuensis and O. kuroiwai. Plant Biotechnology 21:4 275.
- ^ Chu, F., et al. (2006). Taxonomic Status of Ophiorrhiza michelloides (Masam.) X. R. Lo (Rubiaceae) in Taiwan. Taiwania 51:2 143.
External links
- Vascular Plants of Gaoligong Shan, Yunnan, China: Ophiorrhiza
- Darwin, S. P. (1976). The Pacific species of Ophiorrhiza (Rubiaceae). Lyonia 1:2.
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