- Nematode chemoreceptor
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Nematode chemoreceptor, Sra Identifiers Symbol Sra_chemorcpt Pfam PF02117 InterPro IPR000344 Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary Nematode chemoreceptors are chemoreceptors of nematodes.
Animals recognise a wide variety of chemicals using their senses of taste and smell. The nematode Caenorhabditis elegans has only 14 types of chemosensory neuron, yet is able to respond to dozens of chemicals because each neuron detects several stimuli. More than 40 highly divergent transmembrane proteins that could contribute to this functional diversity have been described[1]. Most of the candidate receptor genes are in clusters of similar genes; 11 of these appear to be expressed in small subsets of chemosensory neurons. A single type of neuron can potentially express at least 4 different receptor genes[1]. Some of these might encode receptors for water-soluble attractants, repellents and pheromones, which are divergent members of the G-protein-coupled receptor family[1]. Sequences of the Sra family of C.elegans receptor-like proteins contain 6-7 hydrophobic, putative transmembrane, regions. These can be distinguished from other 7TM proteins (especially those known to couple G-proteins) by their own characteristic TM signatures.
References
This article includes text from the public domain Pfam and InterPro IPR000344
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