NatsiRNA

Natural antisense short interfering RNA (natsiRNA) is a type of siRNA. They are endogenous RNA regulators which are between 21 and 24 nucleotides in length, and are generated from complementary mRNA transcripts which are further processed into siRNA.^[1]

natsiRNA has been implicated in several developmental and response mechanisms in plants, such as pathogen resistance,^[2] salt tolerance ^[3] and cell wall biosynthesis.^[4]

1. ^ Moldovan, D.; Spriggs, A.; Dennis, E. S.; Wilson, I. W. (2010). "The hunt for hypoxia responsive natural antisense short interfering RNAs". Plant signaling & behavior 5 (3): 247–251. PMC 2881268. PMID 20009576. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2881268.  edit
2. ^ Katiyar-Agarwal, S.; Morgan, R.; Dahlbeck, D.; Borsani, O.; Villegas, A.; Zhu, J. -K.; Staskawicz, B. J.; Jin, H. (2006). "A pathogen-inducible endogenous siRNA in plant immunity". Proceedings of the National Academy of Sciences 103 (47): 18002–18007. doi:10.1073/pnas.0608258103. PMC 1693862. PMID 17071740. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1693862.  edit
3. ^ Borsani, O.; Zhu, J.; Verslues, P. E.; Sunkar, R.; Zhu, J. K. (2005). "Endogenous siRNAs Derived from a Pair of Natural cis-Antisense Transcripts Regulate Salt Tolerance in Arabidopsis". Cell 123 (7): 1279–1291. doi:10.1016/j.cell.2005.11.035. PMC 3137516. PMID 16377568. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3137516.  edit
4. ^ Held, M. A.; Penning, B.; Brandt, A. S.; Kessans, S. A.; Yong, W.; Scofield, S. R.; Carpita, N. C. (2008). "Small-interfering RNAs from natural antisense transcripts derived from a cellulose synthase gene modulate cell wall biosynthesis in barley". Proceedings of the National Academy of Sciences 105 (51): 20534–20539. doi:10.1073/pnas.0809408105. PMC 2603254. PMID 19075248. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2603254.  edit