Myelonecrosis

Myelonecrosis is a degenerative change to bone marrow caused primarily by loss of circulation to the bone tissue (ischaemia).^[1]

These changes can be caused by toxic insult, thrombosis, neoplasia or DIC (disseminated intravascular coagulation).

References

1. ^ Prajapati, NC; Singh, T; Gautam, P; Dubey, AP; Choudhury, P; Puri, RK (1994). "Myelonecrosis in acute leukemia". Indian pediatrics 31 (1): 60–4. PMID 7883324.