Mogroside

A mogroside is any of several chemical compounds found in certain plants, such as the fruit of the gourd vine luo han guo (Siraitia grosvenorii). They are glycosides of cucurbitane derivatives.^[1][2][3] They include:

• Mogroside II B ^[2]
• 7-Oxomogroside II E ^[2]
• 11-Deoxymogroside III ^[2]

• 11-Oxomogroside IV A ^[2]

• Mogroside V ^[1]
• 7-Oxomogroside V ^[2]
• 11-Oxo-mogroside V ^[1]

Structural formula of mogroside 5

Most of these compounds are soluble in ethanol.^[2]

Uses

Some mogrosides are natural sweeteners. The pure mogroside mix extracted from the S. grovesnori fruit is 300 times sweeter than sugar. Pure mogroside-5 can be up to 400 times as sweet.

Mogrosides have also been investigated as possible anticancer agents.^[1]

References

1. ^ ^{a b c d} Midori Takasaki, Takao Konoshima, Yuji Murata, Masaki Sugiura, Hoyoku Nishino, Harukuni Tokuda, Kazuhiro Matsumoto, Ryoji Kasai, and Kazuo Yamasaki (2003) "Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori". Cancer Letters, volume 198, pages 37–42
2. ^ ^{a b c d e f g h i j} Naoto Shimizu, Toshihiro Akihisa, Hiroki Kumagai, Christine Miller, Takashi Suzuki, Yumiko Kimura, Harukuni Tokuda (2007) "Characterization of cucurbitane glycosides from the fruit of Momordica grosvenorii with LCMS and their inhibitory effect on Epstein-Barr virus activation". ASMS 2007 poster WPY 399, Agilent Technologies
3. ^ Subhuti Dharmananda (), "Luo Han Guo - Sweet Fruit Used as Sugar Substitute and Medicinal Herb". Website of Institute for Traditional Medicine, Portland, Oregon.

See also

• Normogroside