- MMS22L
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MMS22-like, DNA repair protein Identifiers Symbols MMS22L; C6orf167; DKFZp686C20164; DKFZp781C2113; FLJ46180; KIAA1900; dJ39B17.2 External IDs HomoloGene: 18874 GeneCards: MMS22L Gene Gene Ontology Molecular function • protein binding Cellular component • nucleus
• FACT complex
• MCM complex
• nuclear replication forkBiological process • double-strand break repair via homologous recombination
• DNA repair
• replication fork processingSources: Amigo / QuickGO Orthologs Species Human Mouse Entrez 253714 212377 Ensembl ENSG00000146263 ENSMUSG00000045751 UniProt Q6ZRQ5 B1AUR6 RefSeq (mRNA) NM_198468 NM_199467.2 RefSeq (protein) NP_940870 NP_955761.2 Location (UCSC) Chr 6:
97.59 – 97.73 MbChr 4:
24.42 – 24.53 MbPubMed search [1] [2] Methyl methanesulfonate-sensitivity protein 22-like also known as MMS22-like, DNA repair protein is a protein that in humans is encoded by the MMS22L gene.[1]
References
Further reading
- Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
- Duro E, Lundin C, Ask K, et al. (2010). "Identification of the MMS22L-TONSL complex that promotes homologous recombination.". Mol. Cell 40 (4): 632–44. doi:10.1016/j.molcel.2010.10.023. PMID 21055984.
- OConnell BC, Adamson B, Lydeard JR, et al. (2010). "A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.". Mol. Cell 40 (4): 645–57. doi:10.1016/j.molcel.2010.10.022. PMID 21055985.
- ODonnell L, Panier S, Wildenhain J, et al. (2010). "The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.". Mol. Cell 40 (4): 619–31. doi:10.1016/j.molcel.2010.10.024. PMID 21055983.
- Piwko W, Olma MH, Held M, et al. (2010). "RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.". EMBO J. 29 (24): 4210–22. doi:10.1038/emboj.2010.304. PMID 21113133.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.
Categories:- Human proteins
- Chromosome 6 gene stubs
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