Delayed Gadolinium Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC)

Introduction

Delayed Gadolinium Enhanced Magnetic Resonance Imaging of Cartilage or dGEMRIC measures the fixed charge density of articular cartilage using the Spin-lattice relaxation time.^[1] Current research is investigating the clinical application of dGEMRIC as a quantitative tool for monitoring cartilage function in diseased or repair cartilage.^[2]

dGEMRIC T1 Map of knee cartilage

dGEMRIC T1 Map miliseconds

References

1. ^ Bashir, A; Gray, ML; Boutin, RD; Burstein, D (1997). "Glycosaminoglycan in articular cartilage: in vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging". Radiology 205 (2): 551–8. PMID 9356644.  edit
2. ^ Siversson, C.; Tiderius, C. J.; Neuman, P.; Dahlberg, L.; Svensson, J. (2010). "Repeatability of T1-quantification in dGEMRIC for three different acquisition techniques: Two-dimensional inversion recovery, three-dimensional look locker, and three-dimensional variable flip angle". Journal of Magnetic Resonance Imaging 31 (5): 1203. doi:10.1002/jmri.22159. PMID 20432357.  edit

External links

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798929/
• http://radiology.rsna.org/content/252/3/865.long
• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663352/
• http://www.ajronline.org/cgi/content/full/191/5/1391
• http://onlinelibrary.wiley.com/doi/10.1002/art.23459/full
• http://radiology.rsna.org/content/239/1/201.long
• http://www.ajronline.org/cgi/content/full/182/1/167