CSRP2BP

CSRP2BP
CSRP2 binding protein
Identifiers
Symbols CSRP2BP; ATAC2; CRP2BP; KAT14; MGC15388; PRO1194; dJ717M23.1
External IDs HomoloGene10745 GeneCards: CSRP2BP Gene
Orthologs
Species Human Mouse
Entrez 57325 228714
Ensembl ENSG00000149474 ENSMUSG00000027425
UniProt Q9H8E8 Q8CID0
RefSeq (mRNA) n/a n/a
RefSeq (protein) NP_065397.3 n/a
Location (UCSC) Chr 20:
18.12 – 18.17 Mb
Chr 2:
144.19 – 144.23 Mb
PubMed search [1] [2]
This box: view · protein that in humans is encoded by the CSRP2BP gene.[1]

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described.[1]

References

Further reading

Weiskirchen, R.; Gressner, A. M. (2000). "The Cysteine- and Glycine-Rich LIM Domain Protein CRP2 Specifically Interacts with a Novel Human Protein (CRP2BP)". Biochemical and Biophysical Research Communications 274 (3): 655–663. doi:10.1006/bbrc.2000.3187. PMID 10924333.  edit Wang, Y. -L.; Faiola, F.; Xu, M.; Pan, S.; Martinez, E. (2008). "Human ATAC is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein". Journal of Biological Chemistry 283 (49): 33808–33815. doi:10.1074/jbc.M806936200. PMC 2590711. PMID 18838386. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2590711.  edit Guelman, S.; Kozuka, K.; Mao, Y.; Pham, V.; Solloway, M. J.; Wang, J.; Wu, J.; Lill, J. R. et al. (2008). "The Double-Histone-Acetyltransferase Complex ATAC is Essential for Mammalian Development". Molecular and Cellular Biology 29 (5): 1176–1188. doi:10.1128/MCB.01599-08. PMC 2643826. PMID 19103755. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2643826.  edit Wang, K.; Zhang, H.; Bloss, C. S.; Duvvuri, V.; Kaye, W.; Schork, N. J.; Berrettini, W.; Hakonarson, H. (2010). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa". Molecular Psychiatry 16 (9): 949–959. doi:10.1038/mp.2010.107. PMID 21079607.  edit


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